Results 101 to 110 of about 38,574 (261)

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun   +13 more
wiley   +1 more source

Validation of International Classification of Diseases Code–Based Case Definitions of Immune Checkpoint Inhibitor–Associated Inflammatory Arthritis From Administrative Health Data

open access: yesArthritis &Rheumatology, EarlyView.
Objective Immune checkpoint inhibitors (ICIs) for cancer can lead to immune‐related adverse events, including ICI‐associated inflammatory arthritis (ICI‐IA). There are no validated International Classification of Diseases (ICD) code–based case definitions for ICI‐IA.
Manar Elsayed   +11 more
wiley   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

open access: yesArthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki   +8 more
wiley   +1 more source

A Pragmatic Trial of a Shared Decision‐Making Intervention to Improve Medication Adherence and Outcomes in Systemic Lupus Erythematosus: The HCQ‐SAFE Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective Hydroxychloroquine (HCQ) nonadherence in systemic lupus erythematosus (SLE) stemming from decision complexities can be improved with shared decision‐making (SDM) tools clarifying benefits and harms. This study aimed to develop and evaluate HCQ‐SAFE, a pictogram‐based SDM tool during SLE visits.
Caroline Packee   +8 more
wiley   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo   +7 more
wiley   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

open access: yesArthritis &Rheumatology, Accepted Article.
Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz   +13 more
wiley   +1 more source

Arthroscopic Modified Trapezoid‐Shaped Double‐Row Repair of Medium‐Large‐Sized Rotator Cuff Tears

open access: yesArthroscopy Techniques, EarlyView.
Abstract The double‐pulley double‐row technique has shown many advantages in the treatment of rotator cuff tears in clinics. However, multiple factors affect rotator cuff healing and retearing, including tendon‐to‐bone contact area, repair tension, and gap formation.
Zheng Sun   +6 more
wiley   +1 more source

Impact of Adherence to Golimumab on Disease Flares in Rheumatoid Arthritis: Results from a Canadian Observational Study

open access: yesPatient Preference and Adherence
Louis Bessette,1 Pauline Boulos,2 Regan Arendse,3 Proton Rahman,4 Sam Aseer,4 Thanu Ruban,5,6 Meagan Rachich,7 Francois Nantel,8 Adriana Calce,7 Odalis Asin-Milan,7 Derek Haaland2,9,10 1Department of Medicine, Laval University, Québec, QC, Canada ...
Bessette L   +10 more
doaj  

Anchor‐Based Double‐Row Suture‐Bridge Repair for Stener‐Like Distal Medial Collateral Ligament Lesions of the Knee

open access: yesArthroscopy Techniques, EarlyView.
Abstract Stener‐like distal injuries of the superficial medial collateral ligament (MCL) are characterized by displacement of the distal ligament stump superficial to the pes anserinus fascia, preventing anatomic healing and resulting in persistent valgus and anteromedial rotatory instability.
Logan D. Moews   +6 more
wiley   +1 more source

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