Results 51 to 60 of about 23,835,912 (305)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Quadcopter Trajectory Tracking Control Based on Flatness Model Predictive Control and Neural Network

open access: yesActuators
In this paper, a novel control architecture is proposed in which FMPC couples feedback from model predictive control with feedforward linearization. The proposed approach has the computational advantage of only requiring a convex quadratic program to be ...
Yong Li, Qidan Zhu, Ahsan Elahi
doaj   +1 more source

Jerk and current limited flatness-based open loop control of foveation scanning electrostatic micromirrors

open access: yes, 2022
S.2685-2690This paper describes open loop control measures for performance improvements of electrostatic micromirrors in context with foveation scanning for 3D time-of-flight cameras.
Schroedter, Richard   +2 more
core  

Benchmarking of Flatness-based Control of the Heat Equation [PDF]

open access: yes, 2023
Flatness-based control design is a well established method to generate open-loop control signals. Several articles discuss the application of flatness-based control design of (reaction-) diffusion problems for various scenarios.
Berger, Lothar   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Flatness-Based Nonlinear Control Scheme for Wire Tension Control of Hoisting Systems

open access: yesIEEE Access, 2019
A double-rope winding hoisting system (DRWHS) is usually employed to transport weight or workers in mines usually from ultra-deep underground (>1000m).
Wanshun Zang   +5 more
doaj   +1 more source

Learning Flatness-Based Controller Using Neural Network [PDF]

open access: yesVolume 3, Rapid Fire Interactive Presentations: Advances in Control Systems; Advances in Robotics and Mechatronics; Automotive and Transportation Systems; Motion Planning and Trajectory Tracking; Soft Mechatronic Actuators and Sensors; Unmanned Ground and Aerial Vehicles, 2019
Abstract Publisher’s Note: This paper was selected for publication in ASME Letters in Dynamic Systems and Control. https://www.asmedigitalcollection.asme.org/lettersdynsys/article/doi/10.1115/1.4046776/1082074/Learning-Flatness-Based-Controller-Using ...
Pinhas Ben-Tzvi, Jingyuan Qi, Hailin Ren
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Implementation and Experimental Verification of Flow Rate Control Based on Differential Flatness in a Tilting-Ladle-Type Automatic Pouring Machine

open access: yesApplied Sciences, 2019
In this paper, we study an advanced pouring control system using a tilting-ladle-type automatic pouring machine. In such a machine, it is difficult to precisely pour the molten metal into the pouring basin of the mold, as the outflow from the ladle can ...
Yoshiyuki Noda, Yuta Sueki
doaj   +1 more source

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