Results 71 to 80 of about 4,640,849 (374)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Flatness-Based Nonlinear Control Scheme for Wire Tension Control of Hoisting Systems
IEEE Access, 2019 A double-rope winding hoisting system (DRWHS) is usually employed to transport weight or workers in mines usually from ultra-deep underground (>1000m).
Wanshun Zang +5 more
doaj +1 more source
Autonomous Planning and Robust Control for Wheeled Mobile Robot With Slippage Disturbances Based on Differential Flat [PDF]
, 2023 Yueyue Liu +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Applied Sciences, 2019 In this paper, we study an advanced pouring control system using a tilting-ladle-type automatic pouring machine. In such a machine, it is difficult to precisely pour the molten metal into the pouring basin of the mold, as the outflow from the ladle can ...
Yoshiyuki Noda, Yuta Sueki
doaj +1 more source
Modern Semi-Active Control Schemes for a Suspension with MR Actuator for Vibration Attenuation
Actuators, 2021 This article describes semi-active modern control schemes for a quarter-vehicle suspension with a magnetorheological damper (MRD) to attenuate vibrations and simultaneously improve the passenger comfort and the vehicle road-holding. The first solution is
Kevin Herubiel Floreán-Aquino +4 more
doaj +1 more source
On the computation of $\pi$-flat outputs for differential-delay systems
, 2014 We introduce a new definition of $\pi$-flatness for linear differential delay systems with time-varying coefficients. We characterize $\pi$- and $\pi$-0-flat outputs and provide an algorithm to efficiently compute such outputs.
Antritter, F. +3 more
core +3 more sources
Flatness-Based Adaptive Fuzzy Control Of Spark-Ignited Engines [PDF]
Journal of Artificial Intelligence and Soft Computing Research, 2014 Abstract An adaptive fuzzy controller is designed for spark-ignited (SI) engines, under the constraint that the system's model is unknown. The control algorithm aims at satisfying the H ∞ tracking performance criterion, which means that the influence of the modeling errors and the external disturbances on the tracking ...
Gerasimos G. Rigatos, SIANO, PIERLUIGI
openaire +3 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source