Results 1 to 10 of about 4,683 (221)

Seasonal Changes in the Tetrodotoxin Content of the Flatworm Planocera multitentaculata

open access: yesMarine Drugs, 2017
Tetrodotoxin (TTX) is a potent neurotoxin that acts specifically on voltage-gated sodium channels on excitable membranes of muscle and nerve tissues. The biosynthetic process for TTX is unclear, although marine bacteria are generally thought to be the ...
Shiro Itoi, Itoi Shiro, Sugita Haruo
exaly   +4 more sources

First Detection of Tetrodotoxins in the Cotylean Flatworm Prosthiostomum trilineatum

open access: yesMarine Drugs, 2021
Several polyclad flatworm species are known to contain high levels of tetrodotoxin (TTX), but currently TTX-bearing flatworms seem to be restricted to specific Planocera lineages belonging to the suborder Acotylea.
Rei Suo   +8 more
doaj   +2 more sources

The invasive New Guinea flatworm Platydemus manokwari in France, the first record for Europe: time for action is now [PDF]

open access: yesPeerJ, 2014
Non-indigenous terrestrial flatworms (Platyhelminthes) have been recorded in thirteen European countries. They include Bipalium kewense and Dolichoplana striata that are largely restricted to hothouses and may be regarded as non-invasive species.
Jean-Lou Justine   +4 more
doaj   +3 more sources

Toxic Flatworm Egg Plates Serve as a Possible Source of Tetrodotoxin for Pufferfish

open access: yesToxins, 2019
The pufferfish Takifugu niphobles (at present Takifugu alboplumbeus) possesses highly concentrated tetrodotoxin (TTX), an extremely potent neurotoxin that provides effective protection from predators, at least at the larval stages. However, the source of
Taiki Okabe, Rei Suo, Haruo Sugita
exaly   +3 more sources

Atp8 is in the ground pattern of flatworm mitochondrial genomes

open access: yesBMC Genomics, 2017
Background To date, mitochondrial genomes of more than one hundred flatworms (Platyhelminthes) have been sequenced. They show a high degree of similarity and a strong taxonomic bias towards parasitic lineages.
Bernhard Egger   +2 more
doaj   +2 more sources

Complete mitogenome of the invasive land flatworm Parakontikia ventrolineata, the second Geoplanidae (Platyhelminthes) to display an unusually long cox2 gene

open access: yesMitochondrial DNA. Part B. Resources, 2020
We sequenced the complete mitogenome of the invasive flatworm Parakontikia ventrolineata (Platyhelminthes, order Tricladida, family Geoplanidae). The genome is 17,210 bp long, and displays common unusual characteristics shared with Platydemus manokwari ...
Romain Gastineau, Jean-Lou Justine
doaj   +2 more sources

Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2014
Pharmacological targeting of glutamate-gated chloride channels (GluCls) is a potent anthelmintic strategy, evidenced by macrocyclic lactones that eliminate numerous roundworm infections by activating roundworm GluCls.
Timothy Lynagh   +3 more
doaj   +3 more sources

TTX-Bearing Planocerid Flatworm (Platyhelminthes: Acotylea) in the Ryukyu Islands, Japan

open access: yesMarine Drugs, 2018
Polyclad flatworms comprise a highly diverse and cosmopolitan group of marine turbellarians. Although some species of the genera Planocera and Stylochoplana are known to be tetrodotoxin (TTX)-bearing, there are few new reports.
Shiro Itoi, Haruo Sugita, Itoi Shiro
exaly   +3 more sources

A World of Viruses Nested within Parasites: Unraveling Viral Diversity within Parasitic Flatworms (Platyhelminthes)

open access: yesMicrobiology Spectrum, 2022
Because parasites have an inextricable relationship with their host, they have the potential to serve as viral reservoirs or facilitate virus host shifts.
Nolwenn M. Dheilly   +3 more
doaj   +1 more source

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