Results 141 to 150 of about 38,528 (267)

Beyond red/far‐red sensing: phytochrome perception of the marine light field by microalgae

open access: yesNew Phytologist, Volume 250, Issue 5, Page 2837-2844, June 2026.
Summary Phytochromes (PHYs) are a major group of photoreceptors, described as red and far‐red light sensors in land plants. Recent genomic and metagenomic explorations have revealed the presence of PHYs also in various eukaryotic microalgae originating from distinct endosymbiotic events.
Carole Duchêne   +2 more
wiley   +1 more source

Metabolic Response to Stress Differentiates Heterogeneous Cancer Cells with Varying Metastatic Potential [PDF]

open access: yes, 2017
Intratumoral heterogeneity is ubiquitously present within primary tumors and contributes to intractable behaviors such as metastasis and mutability spatiotemporally.
Alhallak, Kinan
core   +2 more sources

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda   +5 more
wiley   +1 more source

Identification of 2‐Substituted‐3‐Hydroxy‐2,3‐Dihydroquinazolin‐4(1H) Ones as Cell‐Active Inhibitors of KDM4A Lysine Demethylase

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
A novel 3‐hydroxy‐2,3‐dihydroquinazolinone scaffold is identified as a cell‐active KDM4A inhibitor through an orthogonal screening cascade minimizing assay interference. Integrated biochemical, biophysical, and proteomic validation reveals compound 6i as a bona fide binder that increases H3K9 methylation in cells, highlighting both a promising ...
Alessandra Feoli   +13 more
wiley   +1 more source

Direct observation of long-lived radical pair between flavin and guanine in single- and double-stranded DNA-oligomers

open access: yesCommunications Chemistry
The mechanism by which cryptochrome (CRY) proteins are capable of sensing weak magnetic fields (e.g., the geomagnetic field: ~50 μT) was suggested to be mediated by spin-correlated radical pairs (SCRPs) comprising a flavin adenine dinucleotide (FAD ...
Yoshimi Oka   +6 more
doaj   +1 more source

Flavin adenine dinucleotide-capped gold nanoclusters: biocompatible photo-emissive nanomaterial and reservoir of lumichrome. [PDF]

open access: yesNanoscale Adv, 2022
Pérez-Herráez I   +4 more
europepmc   +1 more source

Time‐Resolved Native Mass Spectrometry Reveals Reversible Light‐Driven Oligomerization of Arabidopsis Cryptochrome 1 and Its Antagonism by BIC1

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 21, 18 May 2026.
Time‐resolved native mass spectrometry uncovers the blue‐light‐dependent kinetic mechanism of Arabidopsis CRY1 oligomerization, proceeding sequentially from monomers to dimers and tetramers. ATP promotes assembly, whereas BIC1 actively blocks and disassembles tetramers independent of light, providing mechanistic insight into the regulation of ...
Alicia Just   +8 more
wiley   +1 more source

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