Results 61 to 70 of about 36,247 (268)
Conserved RNA secondary structures in Flaviviridae genomes [PDF]
Journal of General Virology, 2004 Presented here is a comprehensive computational survey of evolutionarily conserved secondary structure motifs in the genomic RNAs of the family Flaviviridae. This virus family consists of the three genera Flavivirus, Pestivirus and Hepacivirus and the group of GB virus C/hepatitis G virus with a currently uncertain taxonomic classification.
Caroline Thurner +3 more
openalex +3 more sources
Blocking Zika virus vertical transmission. [PDF]
, 2018 The outbreak of the Zika virus (ZIKV) has been associated with increased incidence of congenital malformations. Although recent efforts have focused on vaccine development, treatments for infected individuals are needed urgently. Sofosbuvir (SOF), an FDA-
Beltrão-Braga, Patricia CB +23 more
core +2 more sources
Frontiers in Cellular and Infection Microbiology, 2019 Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines.
Megan Chesnut +10 more
doaj +1 more source
Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]
, 2016 In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano +4 more
core +1 more source
Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV) [PDF]
, 2017 The International Committee on Taxonomy of Viruses (ICTV) is charged with the task of developing, refining, and maintaining a universal virus taxonomy.
Dempsey, Donald M. +5 more
core +3 more sources
Cross-Protection of Dengue Virus Infection against Congenital Zika Syndrome, Northeastern Brazil
Emerging Infectious Diseases, 2019 The Zika virus outbreak in Latin America resulted in congenital malformations, called congenital Zika syndrome (CZS). For unknown reasons, CZS incidence was highest in northeastern Brazil; one potential explanation is that dengue virus (DENV)–mediated ...
Celia Pedroso +10 more
doaj +1 more source
Pathogens, 2023 West Nile virus (WNV) is a mosquito-borne pathogen that belongs to the Flavivirus genus (family Flaviviridae) [...]
Francisco Llorente
doaj +1 more source
Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]
, 2014 Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle +3 more
core +1 more source
NTPase/helicase of Flaviviridae: inhibitors and inhibition of the enzyme.
Acta Biochimica Polonica, 2002 RNA nucleoside triphosphatases (NTPase)/helicases represent a large family of proteins that are ubiquitously distributed over a wide range of organisms. The enzymes play essential role in cell development and differentiation, and some of them are involved in transcription and replication of viral single-stranded RNA genomes. The enzymatic activities of
Peter Borowski +6 more
openalex +5 more sources
A novel membrane fusion protein family in Flaviviridae? [PDF]
Trends in Microbiology, 2014 Enveloped viruses must fuse their lipid membrane to a cellular membrane to deliver their genome into the cytoplasm for replication. Viral envelope proteins catalyze this critical membrane fusion event. They fall into three distinct structural classes.
Li, Yue, Modis, Yorgo
openaire +4 more sources