Arboviruses and the challenge to establish systemic and persistent infections in competent mosquito vectors : the interaction with the RNAi mechanism [PDF]
Arboviruses are capable to establish long-term persistent infections in mosquitoes that do not affect significantly the physiology of the insect vectors. Arbovirus infections are controlled by the RNAi machinery via the production of viral siRNAs and the
Kolliopoulou, Anna+3 more
core +1 more source
Background Zika virus (ZIKV), a member of the Flaviviridae family, has caused massive outbreaks of infection in tropical areas over the last decade and has now begun spreading to temperate countries.
Yannick Tréguier+7 more
doaj +1 more source
Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain.
Ortrud Monika Barth+3 more
doaj +1 more source
Altered m6A modification of specific cellular transcripts affects Flaviviridae infection
The RNA modification N6-methyladenosine (m6A) can modulate mRNA fate and thus affect many biological processes. We analyzed m6A modification across the transcriptome following infection by dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV ...
Nandan S. Gokhale+6 more
semanticscholar +1 more source
The core protein of classical Swine Fever virus is dispensable for virus propagation in vitro. [PDF]
Core protein of Flaviviridae is regarded as essential factor for nucleocapsid formation. Yet, core protein is not encoded by all isolates (GBV- A and GBV- C).
Christiane Riedel+8 more
doaj +1 more source
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A.+5 more
core +3 more sources
Flaviviridae Viruses and Oxidative Stress: Implications for Viral Pathogenesis
Oxidative stress is induced once the balance of generation and neutralization of reactive oxygen species (ROS) is broken in the cell, and it plays crucial roles in a variety of natural and diseased processes.
Zhenzhen Zhang, Liang Rong, Yi-Ping Li
semanticscholar +1 more source
Togaviridae and Flaviviridae: The Alphavirases and Flaviviruses [PDF]
Diseases: Yellow fever, dengue, St. Louis encephalitis, Japanese encephalitis, Wes- selsbron, tick-borne encephalitis, louping ill, Kyasanur Forest disease, other tick- borne hemorrhagic fevers, Murray Valley encephalitis, Rocio encephalitis, equine encephalitides (eastern, western, Venezuelan), chikungunya, o’nyong-nyong, Ross River, Mayaro, Sindbis ...
Charles H. Calisher, Thomas P. Monath
openaire +1 more source
Potential for Protein Kinase Pharmacological Regulation in Flaviviridae Infections
Protein kinases (PKs) are enzymes that catalyze the transfer of the terminal phosphate group from ATP to a protein acceptor, mainly to serine, threonine, and tyrosine residues.
A. Blázquez, J. Saiz
semanticscholar +1 more source
Insect-transmitted vertebrate viruses: Flaviviridae [PDF]
The Flaviviridae include almost 70 viruses, nearly half of which have been associated with human disease. These viruses are among the most important arthropod-borne viruses worldwide and include dengue, yellow fever, and Japanese encephalitis viruses.
Lauren C. Iacono-Connors+1 more
openaire +3 more sources