Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens
Nature, 2016 The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually worldwide. No approved antivirals are available to
C. Marceau +10 more
semanticscholar +1 more source
Atypical Porcine Pestivirus Molecular Evolution within a Persistently Infected Swine Farm
Proceedings, 2020 Atypical porcine pestivirus (APPV) is a single stranded RNA virus from the family Flaviviridae. [...]
Alba Folgueiras-González +5 more
doaj +1 more source
Zika virus infection: a public health emergency! [PDF]
, 2017 Zika virus belongs to the family of Flaviviridae. The Flaviviridae family also includes other human pathogens like West Nile virus (WNV), Yellow fever virus (YFV), mosquito transmitted Dengue virus (DENV), Tick borne encephalitic virus (TBEV) and ...
Khan, Ramsha +2 more
core +1 more source
A library of infectious hepatitis C viruses with engineered mutations in the E2 gene reveals growth-adaptive mutations that modulate interactions with scavenger receptor class B type I [PDF]
, 2016 While natural hepatitis C virus (HCV) infection results in highly diverse quasispecies of related viruses over time, mutations accumulate more slowly in tissue culture, in part because of the inefficiency of replication in cells.
Chen, Kevin +8 more
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Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]
, 2017 The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J. +3 more
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Vaccine development for mosquito-borne viral diseases
Frontiers in Immunology, 2023 Mosquito-borne viral diseases are a group of viral illnesses that are predominantly transmitted by mosquitoes, including viruses from the Togaviridae and Flaviviridae families.
Zhiwei Huang +7 more
doaj +1 more source
Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review
Global Challenges, EarlyView.Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze +8 more
wiley +1 more source
The First Flaviviridae Symposium
Intervirology, 1997 The first annual Flaviviridae Symposium, sponsored by ICN Pharmaceuticals Inc., was held in Lyon, France, on 9 October, 1997, to communicate current understanding on the Flaviviridae. This multidisciplinary symposium attracted over 300 international delegates and presentations covered virology, viral pathogenesis, potential therapies and strategies for
C. Trépo +3 more
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Cadernos de Saúde Pública, 2009 O objetivo foi avaliar a prevalência de anticorpos para arbovírus na área de influência do Projeto Juruti antes da exploração mineral local. Foram examinados 1.597 soros humanos e 85 de animais silvestres.
Ana Cecilia Ribeiro Cruz +10 more
doaj +1 more source
Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes
, 2008 By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin +20 more
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