Results 81 to 90 of about 39,219 (283)

Vaccine development for mosquito-borne viral diseases

Frontiers in Immunology, 2023
Mosquito-borne viral diseases are a group of viral illnesses that are predominantly transmitted by mosquitoes, including viruses from the Togaviridae and Flaviviridae families.
Zhiwei Huang, Yuxuan Zhang, Hongyu Li, Jiajie Zhu, Wanchen Song, Keda Chen, Yanjun Zhang, Yongliang Lou   +7 more
doaj   +1 more source

Optimal control of a dengue epidemic model with vaccination [PDF]

, 2011
We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used.
Delfim F. M. Torres, Helena Sofia Rodrigues, M. Teresa, T. Monteiro   +3 more
core   +2 more sources

Potential for Protein Kinase Pharmacological Regulation in Flaviviridae Infections

International Journal of Molecular Sciences, 2020
Protein kinases (PKs) are enzymes that catalyze the transfer of the terminal phosphate group from ATP to a protein acceptor, mainly to serine, threonine, and tyrosine residues.
A. Blázquez, J. Saiz
semanticscholar   +1 more source

The Zika outbreak of the 21st century. [PDF]

, 2016
The Zika virus outbreak has captivated the attention of the global audience and information has spread rapidly and wildly through the internet and other media channels.
Ansari, Aftab, Chang, Christopher, Gershwin, M Eric, Ortiz, Kristina   +3 more
core   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

The First Flaviviridae Symposium

Intervirology, 1997
The first annual Flaviviridae Symposium, sponsored by ICN Pharmaceuticals Inc., was held in Lyon, France, on 9 October, 1997, to communicate current understanding on the Flaviviridae. This multidisciplinary symposium attracted over 300 international delegates and presentations covered virology, viral pathogenesis, potential therapies and strategies for
C. Trépo, F.N. Zeytin, W.H. Gerlich, John M. Vierling   +3 more
openaire   +2 more sources

Vigilância sorológica para arbovírus em Juruti, Pará, Brasil Serological survey for arboviruses in Juruti, Pará State, Brazil

Cadernos de Saúde Pública, 2009
O objetivo foi avaliar a prevalência de anticorpos para arbovírus na área de influência do Projeto Juruti antes da exploração mineral local. Foram examinados 1.597 soros humanos e 85 de animais silvestres.
Ana Cecilia Ribeiro Cruz, Assis do Socorro Correa dos Prazeres, Eliana Colares Gama, Maxwell Furtado de Lima, Raimunda do Socorro Silva Azevedo, Lívia Medeiros Neves Casseb, Joaquim Pinto Nunes Neto, Lívia Carício Martins, Jannifer Oliveira Chiang, Sueli Guerreiro Rodrigues, Pedro Fernando da Costa Vasconcelos   +10 more
doaj   +1 more source

Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. [PDF]

, 2018
Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays.
Duggan, Brendan M, Emwas, Abdul-Hamid, Gerwick, William H, Kharbatia, Najeh, Kremb, Stephan, O'Rourke, Aubrie, Raji, Misjudeen, Sioud, Salim, Voolstra, Christian R   +8 more
core   +3 more sources

“Molecular Docking and Dynamic Studies of Amide Derivatives from Cinnamic Acid with Potential Anti‐Dengue Virus Activity”

ChemistryOpen, EarlyView.
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados, Manuel Alejandro Hernández‐Serda, Omar Joel Villegas‐Solís, Víctor Hugo Vázquez‐Valadez, Aldo Yoshio Alarcón‐López, Pablo A. Martínez‐Soriano, Jaqueline Ramos‐Sánchez, Tannya Karen Castro‐Jiménez, José Bustos‐Arriaga, Enrique Angeles   +9 more
wiley   +1 more source

GB virus C viremia and anti-E2 antibody response among hemodialysis patients in Gorgan, Iran [PDF]

, 2014
Background: GB Virus C is a blood-borne virus and a member of Flaviviridae, like hepatitis C that is distributed globally and puts hemodialysis patients at high risk of developing liver disease.
Bazouri, M., Hashemi, P., Kelishadi, M., Mojerloo, M., Moradi, A., Saeedi, A., Samadi, S., Tabarraei, A.   +7 more
core   +1 more source