Results 81 to 90 of about 35,886 (277)

Unravelling Electronic Structure and Molecular Vibrations of Proteins in Virus Using Novel Correlated Plasmon‐Enhanced Raman Spectroscopy With Machine Learning

Small, EarlyView.
A novel, non‐destructive, stable, direct technique, named correlated plasmon‐enhanced Raman spectroscopy (CP‐ERS), which is based on a newly‐developed highly oriented single crystalline gold quantum dots (HOSG‐QDs) chip, is developed to measure and quantify molecular vibrations and electronic structure of analytes.
Vashu Kamboj, Shermine Ho, Fakhriedzwan Idris, Donald Heng Rong Ting, Khadijah Bte Kamsari Sanuh, Sylvie Alonso, Eng Soon Tok, Andrivo Rusydi   +7 more
wiley   +1 more source

ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. [PDF]

, 2018
BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation ...
Fu, Z, Hu, Q, Ke, X, Li, P, Liu, Y, Sun, J, Tan, Z, Wang, H, Zhang, W, Zhang, Y, Zheng, C, Zheng, Z   +11 more
core   +1 more source

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

Small, EarlyView.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins, Louise Bondeelle, Arnaud Charles‐Antoine Zwygart, Thais Melquiades de Lima, Juliano de Paula Souza, Han Kang Tee, Fernando Chahud, Eurico de Arruda Neto, Francesco Stellacci, Renata Fonseca Vianna Lopez, Caroline Tapparel   +10 more
wiley   +1 more source

Host Cell Transcriptome Profile during Wild-Type and Attenuated Dengue Virus Infection [PDF]

, 2013
10.1371/journal.pntd.0002107PLoS Neglected Tropical ...
A Becerra, A Sabchareon, A Wilder-Smith, AJ Matlin, AM Nasirudeen, AM Ward, AW Tai, B Malewicz, B Pulendran, BJ Blencowe, C Balas, C Le Sommer, C Trapnell, C Trapnell, CP Simmons, CS Villas-Boas, CY Huang, CY Yu, D Normile, DJ Gubler, DJ Gubler, DS Deluca, DS Shepard, EJ Nascimento, Eng Eong Ooi, ET Wang, Eva Harris, GF Silveira, HA Tissera, HT Long, HY Huang, I Umareddy, J Fink, J Pena, JA Suaya, JC Marioni, JL Kyle, Kenneth C. Goh, KJ Liew, LR Carrasco, LT Hoang, M Le Breton, MD Fernandez-Garcia, ME Beatty, MJ Schreiber, MM Moreno-Altamirano, MN Krishnan, October M. Sessions, OM Sessions, P Loke, Patrick Tan, Q Li, RV Warke, S Ubol, SB Halstead, Steve Rozen, T Tolfvenstam, TM Conceicao, Y Katz, Ying Tan, Yujing Liu, Z Wang   +61 more
core   +4 more sources

ICTV Virus Taxonomy Profile: Flaviviridae

Journal of General Virology, 2017
The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus. The majority of known members in the genus Flavivirus are arthropod borne, and many are important human and veterinary ...
Simmonds, P, Becher, P, Bukh, J, Gould, E, Meyers, G, Monath, T, Muerhoff, S, Pletnev, A, Rico-Hesse, R, Smith, D, Stapleton, J, Consortium,, Ictv Report   +11 more
openaire   +2 more sources

Does a decision support tool designed to depict West Nile virus risk explain variation in ruffed grouse Bonasa umbellus use of managed forests?

Wildlife Biology, EarlyView.
Infectious diseases are commonly cited as significant contributors to wildlife population declines. It is, therefore, important to investigate the extent to which tools designed to mitigate the effects of infectious diseases explain wildlife responses to habitat management.
Jacob Goldman, Darin J. McNeil, Lauren M. Chronister, Randall Koleck, Samuel Lapp, Jeffery T. Larkin, Reina Tyl, Justin Kitzes, Jeffery L. Larkin   +8 more
wiley   +1 more source

A Review on The Pathogenesis of Cardiovascular Disease of Flaviviridea Viruses Infection

Viruses
Members of the Flaviviridae family, encompassing the Flavivirus and Hepacivirus genera, are implicated in a spectrum of severe human pathologies. These diseases span a diverse spectrum, including hepatitis, vascular shock syndrome, encephalitis, acute ...
Tie-Hua Yang, Wen-Cong Gao, Xin Ma, Qian Liu, Pan-Pan Pang, Yong-Tang Zheng, Yinnong Jia, Chang-Bo Zheng   +7 more
doaj   +1 more source

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]

, 2006
In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi, Baumert, Thomas, Chisari, Francis V, Kapadia, Sharookh B, McKeating, Jane A   +4 more
core   +2 more sources

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]

, 1989
Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S., Lenches, Edith M., Rice, Charles M., Strauss, Ellen G., Strauss, James H.   +4 more
core