Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
, 2011 We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A. +5 more
core +3 more sources
Clinical Case Reports, 2018 Key Clinical Message In the 80s, dengue viruses type 1 and 4 (DENV‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV‐1 introduction in the state of Rio de Janeiro (RJ) in mid‐1980s, that dengue became a nationwide ...
Fernanda de Bruycker‐Nogueira +5 more
doaj +1 more source
Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review
Asian Pacific Journal of Tropical Medicine, 2023 Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin +3 more
doaj +1 more source
Human case of West Nile neuroinvasive disease in Portugal, summer 2015 [PDF]
, 2015 A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human ...
Alves, M. J. +7 more
core +1 more source
Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]
, 2018 During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M +17 more
core +2 more sources
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
, 2000 We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi +3 more
core +2 more sources
Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes
Pathogens, 2019 Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins.
Hussin A. Rothan, Mukesh Kumar
doaj +1 more source
Generation and Implementation of Reporter BHK-21 Cells for Live Imaging of Flavivirus Infection
Bio-Protocol, 2021 The genus Flavivirus within the family Flaviviridae includes many viral species of medical importance, such as yellow fever virus (YFV), Zika virus (ZIKV), and dengue virus (DENV), among others.
Jorge Arias-Arias +1 more
doaj +1 more source
ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. [PDF]
, 2018 BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation ...
Fu, Z +11 more
core +1 more source