Results 31 to 40 of about 47,733 (260)

Flavivirus enzymes and their inhibitors

open access: yes, 2021
Flaviviruses such as dengue, Japanese encephalitis, West Nile, Yellow Fever and Zika virus, cause viral hemorrhagic fever and encephalitis in humans. However, antiviral therapeutics to treat or prevent flavivirus infections are not yet available. Thus, there is pressing need to develop therapeutics and vaccines that target flavivirus infections.
Marc C. Morais   +2 more
openaire   +4 more sources

30 years of dengue fatal cases in Brazil: a laboratorial-based investigation of 1047 cases

open access: yesBMC Infectious Diseases, 2018
Background Dengue viruses (DENV) have emerged and reemerged in Brazil in the past 30 years causing explosive epidemics. The disease may range from clinically asymptomatic infections to severe and fatal outcomes.
Priscila Conrado Guerra Nunes   +14 more
doaj   +1 more source

Serological Diagnosis of Flavivirus-Associated Human Infections

open access: yesDiagnostics, 2020
Arthropod-borne viruses (arboviruses) belonging to the Flavivirus genus of the Flaviviridae family, are a major public health threat in tropical and subtropical regions, and have recently become a medical concern in temperate zones. Most flaviviruses are
Didier Musso, Philippe Desprès
doaj   +1 more source

Flavivirus NS1 and Its Potential in Vaccine Development

open access: yesVaccines, 2021
The Flavivirus genus contains many important human pathogens, including dengue, Japanese encephalitis (JE), tick-borne encephalitis (TBE), West Nile (WN), yellow fever (YF) and Zika (ZIK) viruses.
Kassandra L. Carpio, Alan D. T. Barrett
doaj   +1 more source

Two avian Plasmodium species trigger different transcriptional responses on their vector Culex pipiens

open access: yesMolecular Ecology, EarlyView., 2023
Abstract Malaria is a mosquito‐borne disease caused by protozoans of the genus Plasmodium that affects both humans and wildlife. The fitness consequences of infections by avian malaria are well known in birds, however, little information exists on its impact on mosquitoes.
Marta Garrigós   +4 more
wiley   +1 more source

Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]

open access: yes, 2017
The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J.   +3 more
core   +1 more source

Predicting wildlife reservoirs and global vulnerability to zoonotic Flaviviruses. [PDF]

open access: yes, 2018
Flaviviruses continue to cause globally relevant epidemics and have emerged or re-emerged in regions that were previously unaffected. Factors determining emergence of flaviviruses and continuing circulation in sylvatic cycles are incompletely understood.
Doyle, Megan M   +5 more
core   +2 more sources

Flavivirus Susceptibility in Aedes aegypti [PDF]

open access: yesArchives of Medical Research, 2002
Aedes aegypti is the primary vector of yellow fever (YF) and dengue fever (DF) flaviviruses worldwide. In this review we focus on past and present research on genetic components and environmental factors in Aedes aegypti that appear to control flavivirus transmission. We review genetic relationships among Ae.
Black, William C.   +8 more
openaire   +3 more sources

Culex flavivirus infection in a Culex pipiens mosquito colony and its effects on vector competence for Rift Valley fever phlebovirus

open access: yesParasites & Vectors, 2018
Background Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito populations. The influence of Culex flavivirus on Rift
Sandra Talavera   +5 more
doaj   +1 more source

Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review

open access: yesAsian Pacific Journal of Tropical Medicine, 2023
Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin   +3 more
doaj   +1 more source

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