Results 31 to 40 of about 68,853 (304)
Memory T Cells in Flavivirus Vaccination [PDF]
Vaccines, 2018 Flaviviruses include many medically important viruses, such as Dengue virus (DENV), Japanese encephalitis (JEV), tick-borne encephalitis (TBEV), West Nile (WNV), yellow fever (YFV), and Zika viruses (ZIKV). Currently, there are licensed human vaccines for DENV, JEV, TBEV and YFV, but not for WNV or ZIKV.
Guangyu Li, Cody Teleki, Tian Wang
openaire +3 more sources
Viruses, 2021 The Flavivirus genus includes a number of important viruses that are pathogenic to humans and animals and are responsible for outbreaks across the globe.
Vinicius Pinho dos Reis +4 more
doaj +1 more source
Compartmentalized replication organelle of flavivirus at the ER and the factors involved
Cellular and Molecular Life Sciences, 2021 Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat to human health. Flaviviruses replicate in compartmentalized replication organelles derived from the host endoplasmic reticulum (ER).
Y. Ci, Lei Shi
semanticscholar +1 more source
30 years of dengue fatal cases in Brazil: a laboratorial-based investigation of 1047 cases
BMC Infectious Diseases, 2018 Background Dengue viruses (DENV) have emerged and reemerged in Brazil in the past 30 years causing explosive epidemics. The disease may range from clinically asymptomatic infections to severe and fatal outcomes.
Priscila Conrado Guerra Nunes +14 more
doaj +1 more source
Nature Communications, 2021 The epidemic emergence of relatively rare and geographically isolated flaviviruses adds to the ongoing disease burden of viruses such as dengue. Structural analysis is key to understand and combat these pathogens.
J. Hardy +10 more
semanticscholar +1 more source
Flavivirus enzymes and their inhibitors
, 2021 Flaviviruses such as dengue, Japanese encephalitis, West Nile, Yellow Fever and Zika virus, cause viral hemorrhagic fever and encephalitis in humans. However, antiviral therapeutics to treat or prevent flavivirus infections are not yet available. Thus, there is pressing need to develop therapeutics and vaccines that target flavivirus infections.
Marc C. Morais +2 more
openaire +4 more sources
Roles of Non-Structural Protein 4A in Flavivirus Infection
Viruses, 2021 Infections with viruses in the genus Flavivirus are a worldwide public health problem. These enveloped, positive sense single stranded RNA viruses use a small complement of only 10 encoded proteins and the RNA genome itself to remodel host cells to ...
Paeka Klaitong, Duncan R. Smith
semanticscholar +1 more source
A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]
, 2017 The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S +4 more
core +5 more sources
Genome-Wide CRISPR Screen Identifies RACK1 as a Critical Host Factor for Flavivirus Replication
Journal of Virology, 2021 Cellular factors are critical in all facets of viral lifecycles, where overlapping interactions between the virus and host can be exploited as possible avenues for the development of antiviral therapeutics.
Byron Shue +10 more
semanticscholar +1 more source
Flavivirus Susceptibility in Aedes aegypti [PDF]
Archives of Medical Research, 2002 Aedes aegypti is the primary vector of yellow fever (YF) and dengue fever (DF) flaviviruses worldwide. In this review we focus on past and present research on genetic components and environmental factors in Aedes aegypti that appear to control flavivirus transmission. We review genetic relationships among Ae.
Black, William C. +8 more
openaire +3 more sources