Results 31 to 40 of about 15,113 (160)
30 years of fatal dengue cases in Brazil: a review
Background Over the last 30 years, extensive dengue epidemics have occurred in Brazil, characterized by emergences and re-emergences of different serotypes, a change in the epidemiological profile and an increase in the number of severe and fatal cases ...
Priscila Conrado Guerra Nunes+5 more
doaj +1 more source
Detection of a new insect flavivirus and isolation of
Background During recent years, numerous novel ‘insect flaviviruses’ have been discovered in natural mosquito populations. In a previous study we described the presence of flavivirus DNA sequences integrated in Aedes albopictus (Asian tiger mosquito ...
Roiz David+9 more
doaj +1 more source
Seeking Flavivirus Cross-Protective Immunity
The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco+4 more
doaj +1 more source
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
Transmission from an infected mosquito to a host is an essential process in the life cycle of mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva facilitates viral transmission. Here we find that a saliva-specific protein,
P. Sun+11 more
semanticscholar +1 more source
Generation and Implementation of Reporter BHK-21 Cells for Live Imaging of Flavivirus Infection
The genus Flavivirus within the family Flaviviridae includes many viral species of medical importance, such as yellow fever virus (YFV), Zika virus (ZIKV), and dengue virus (DENV), among others.
Jorge Arias-Arias+1 more
doaj +1 more source
Anti-flavivirus Properties of Lipid-Lowering Drugs
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human pathogens, an effective vaccine or antiviral treatment against them is not available. Hence, the search for new strategies to control flavivirus infections is essential.
Carlos Noe Farfán-Morales+8 more
semanticscholar +1 more source
Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes
Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins.
Hussin A. Rothan, Mukesh Kumar
doaj +1 more source
Mosquito-borne diseases (MBDs), including those caused by flaviviruses, remain human health problems for developing and urbanizing economies. This cross-sectional study examined risks of flavivirus exposure through a survey regarding knowledge and ...
Long Pham-Thanh+10 more
doaj +1 more source
Nucleic acid test (NAT), most typically quantitative PCR, is one of the standard methods for species specific flavivirus diagnosis. Semi-comprehensive NATs such as pan-flavivirus PCR which covers genus Flavivirus are also available; however, further ...
Patrick Reteng+12 more
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Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan+15 more
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