Results 41 to 50 of about 45,475 (259)
Parasites & Vectors, 2018 Background Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito populations. The influence of Culex flavivirus on Rift
Sandra Talavera +5 more
doaj +1 more source
Predicting wildlife reservoirs and global vulnerability to zoonotic Flaviviruses. [PDF]
, 2018 Flaviviruses continue to cause globally relevant epidemics and have emerged or re-emerged in regions that were previously unaffected. Factors determining emergence of flaviviruses and continuing circulation in sylvatic cycles are incompletely understood.
Doyle, Megan M +5 more
core +2 more sources
30 years of fatal dengue cases in Brazil: a review
BMC Public Health, 2019 Background Over the last 30 years, extensive dengue epidemics have occurred in Brazil, characterized by emergences and re-emergences of different serotypes, a change in the epidemiological profile and an increase in the number of severe and fatal cases ...
Priscila Conrado Guerra Nunes +5 more
doaj +1 more source
TRIMming Flavivirus Infection [PDF]
Cell Host & Microbe, 2011 Tripartite motif (TRIM) proteins are novel players in antiviral innate immunity. In this issue of Cell Host & Microbe,Taylor et al. (2011) discover the mechanism of action of TRIM79α and show that this interferon-induced protein restricts tick-borne flaviviruses by targeting the viral polymerase for degradation.
openaire +3 more sources
The dual regulation of apoptosis by Flavivirus [PDF]
Frontiers in Microbiology, 2020 Apoptosis is a form of programmed cell death, which maintains cellular homeostasis by eliminating pathogen-infected cells. It contains three signaling pathways: death receptor pathway, mitochondria-mediated pathway and endoplasmic reticulum pathway. Its importance in host defenses is highlighted by the observation that many viruses evade, hinder or ...
Yuhong Pan +12 more
openaire +6 more sources
Viruses, 2021 Flaviviruses are known to cause a variety of diseases in humans in different parts of the world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore new drug targets must be explored.
Abdul Wahaab +8 more
doaj +1 more source
An optimal control model of mosquito reduction management in a dengue endemic region [PDF]
International Journal of Biomathematics, 7(5): 7, 1450056 (2014), 2015 Aedes aegypti is known as the responsible vector transmitting dengue flavivirus. Unavailability of medication to cure the transmission of the virus in the human blood becomes a global health issue in recent decades. World epidemiologists are encouraged to focus on the investigation over the effective and inexpensive way to prevent dengue transmission ...
arxiv +1 more source
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
, 2017 Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
Zika virus: New clinical syndromes and its emergence in the western hemisphere [PDF]
, 2016 Zika virus (ZIKV) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern.
Brazilian Medical Genetics Society–Zika Embryopathy Task Force +9 more
core +3 more sources
Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. [PDF]
, 2009 © 2009 Wang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Béatrice Nal +10 more
core +6 more sources