The dual regulation of apoptosis by Flavivirus [PDF]
Frontiers in Microbiology, 2020 Apoptosis is a form of programmed cell death, which maintains cellular homeostasis by eliminating pathogen-infected cells. It contains three signaling pathways: death receptor pathway, mitochondria-mediated pathway and endoplasmic reticulum pathway. Its importance in host defenses is highlighted by the observation that many viruses evade, hinder or ...
Yuhong Pan +12 more
openaire +6 more sources
Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review
Asian Pacific Journal of Tropical Medicine, 2023 Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin +3 more
doaj +1 more source
Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]
, 2017 Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas +5 more
core +2 more sources
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
, 2011 We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A. +5 more
core +3 more sources
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
, 2000 We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi +3 more
core +2 more sources
Human case of West Nile neuroinvasive disease in Portugal, summer 2015 [PDF]
, 2015 A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human ...
Alves, M. J. +7 more
core +1 more source
Journal of General Virology, 2014 The 5′ end of eukaryotic mRNA contains the type-1 (m7GpppNm) or type-2 (m7GpppNmNm) cap structure. Many viruses have evolved various mechanisms to develop their own capping enzymes (e.g. flavivirus and coronavirus) or to ‘steal’ caps from host mRNAs (e.g. influenza virus).
Roland Züst +5 more
openaire +3 more sources
Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes
Pathogens, 2019 Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins.
Hussin A. Rothan, Mukesh Kumar
doaj +1 more source
Generation and Implementation of Reporter BHK-21 Cells for Live Imaging of Flavivirus Infection
Bio-Protocol, 2021 The genus Flavivirus within the family Flaviviridae includes many viral species of medical importance, such as yellow fever virus (YFV), Zika virus (ZIKV), and dengue virus (DENV), among others.
Jorge Arias-Arias +1 more
doaj +1 more source
Flavivirus RNA in Phlebotomine Sandflies [PDF]
Vector-Borne and Zoonotic Diseases, 2010 Sandfly-transmitted phleboviruses, such as Toscana, sandfly fever Sicilian, and sandfly fever Naples, can cause human disease and circulate at high rates in Mediterranean countries. Previous studies have also established that viruses other than phleboviruses may be detected in and isolated from sand flies. The recent detection and isolation (in a large
/Moureau, Grégory +5 more
openaire +3 more sources