Results 41 to 50 of about 45,949 (202)
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Science Advances, 2021 The structure of an infectious immature flavivirus redefines viral architecture and maturation. Flaviviruses are the cause of severe human diseases transmitted by mosquitoes and ticks.
N. Newton +12 more
semanticscholar +1 more source
Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism
Cell Reports, 2019 SUMMARY Flaviviruses cause systemic or neurotropic-encephalitic pathology in humans. The flavivirus nonstructural protein 1 (NS1) is a secreted glycoprotein involved in viral replication, immune evasion, and vascular leakage during dengue virus infection.
H. Puerta-Guardo +8 more
semanticscholar +1 more source
Roles of Non-Structural Protein 4A in Flavivirus Infection
Viruses, 2021 Infections with viruses in the genus Flavivirus are a worldwide public health problem. These enveloped, positive sense single stranded RNA viruses use a small complement of only 10 encoded proteins and the RNA genome itself to remodel host cells to ...
Paeka Klaitong, Duncan R. Smith
semanticscholar +1 more source
Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes
Pathogens, 2019 Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins.
Hussin A. Rothan, Mukesh Kumar
doaj +1 more source
Generation and Implementation of Reporter BHK-21 Cells for Live Imaging of Flavivirus Infection
Bio-Protocol, 2021 The genus Flavivirus within the family Flaviviridae includes many viral species of medical importance, such as yellow fever virus (YFV), Zika virus (ZIKV), and dengue virus (DENV), among others.
Jorge Arias-Arias +1 more
doaj +1 more source
Journal of General Virology, 2014 The 5′ end of eukaryotic mRNA contains the type-1 (m7GpppNm) or type-2 (m7GpppNmNm) cap structure. Many viruses have evolved various mechanisms to develop their own capping enzymes (e.g. flavivirus and coronavirus) or to ‘steal’ caps from host mRNAs (e.g. influenza virus).
Hongping, Dong +5 more
openaire +2 more sources
Seeking Flavivirus Cross-Protective Immunity
Frontiers in Immunology, 2019 The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco +4 more
doaj +1 more source
TRIMming Flavivirus Infection [PDF]
Cell Host & Microbe, 2011 Tripartite motif (TRIM) proteins are novel players in antiviral innate immunity. In this issue of Cell Host & Microbe,Taylor et al. (2011) discover the mechanism of action of TRIM79α and show that this interferon-induced protein restricts tick-borne flaviviruses by targeting the viral polymerase for degradation.
openaire +2 more sources
Tropical Medicine and Infectious Disease, 2022 Mosquito-borne diseases (MBDs), including those caused by flaviviruses, remain human health problems for developing and urbanizing economies. This cross-sectional study examined risks of flavivirus exposure through a survey regarding knowledge and ...
Long Pham-Thanh +10 more
doaj +1 more source