Results 51 to 60 of about 53,374 (257)

Seeking Flavivirus Cross-Protective Immunity

Frontiers in Immunology, 2019
The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco, Letícia Tsieme Gushi, Wilson Barros Luiz, Jaime Henrique Amorim, Jaime Henrique Amorim   +4 more
doaj   +1 more source

Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities. [PDF]

, 2018
During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women.
Aagaard, Kjersti M, Castro, Eumenia CC, Chiu, Charles Y, Giavedoni, Luis, Hodara, Vida L, Layne-Colon, Donna, Li, Tony, Martyn, Calla, Parodi, Laura M, Patterson, Jean L, Reyes, Kevin, Rutherford, Julienne, Seferovic, Maxim, Suter, Melissa A, Sánchez-San Martín, Claudia, Tamhankar, Manasi, Tardif, Suzette D, Yagi, Shigeo   +17 more
core   +2 more sources

ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. [PDF]

, 2018
BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation ...
Fu, Z, Hu, Q, Ke, X, Li, P, Liu, Y, Sun, J, Tan, Z, Wang, H, Zhang, W, Zhang, Y, Zheng, C, Zheng, Z   +11 more
core   +1 more source

Zoonotic Flavivirus Exposure in Peri-Urban and Suburban Pig-Keeping in Hanoi, Vietnam, and the Knowledge and Preventive Practices of Pig Farmers

Tropical Medicine and Infectious Disease, 2022
Mosquito-borne diseases (MBDs), including those caused by flaviviruses, remain human health problems for developing and urbanizing economies. This cross-sectional study examined risks of flavivirus exposure through a survey regarding knowledge and ...
Long Pham-Thanh, Thang Nguyen-Tien, Ulf Magnusson, Vuong Nghia Bui, Anh Ngoc Bui, Åke Lundkvist, Duoc Trong Vu, Son Hai Tran, Minh Xuan Can, Hung Nguyen-Viet, Johanna F. Lindahl   +10 more
doaj   +1 more source

Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection [PDF]

, 2017
Tick-borne encephalitis virus (TBEV) is a member of the genus Flavivirus. It can cause serious infections in humans that may result in encephalitis/meningoencephalitis. Although several studies have described the involvement of specific genes in the host
Grubhoffer, Libor, Gu, Quan, Kohl, Alain, Schnettler, Esther, Selinger, Martin, Tong, Lily, Wilkie, Gavin S.   +6 more
core   +2 more sources

Blocking Zika virus vertical transmission. [PDF]

, 2018
The outbreak of the Zika virus (ZIKV) has been associated with increased incidence of congenital malformations. Although recent efforts have focused on vaccine development, treatments for infected individuals are needed urgently. Sofosbuvir (SOF), an FDA-
Beltrão-Braga, Patricia CB, Corbett, Kevin D, Cugola, Fernanda R, Fernandes, Isabella R, Herai, Roberto H, Huang, Chun-Teng, Kolar, Matthew J, Macia, Angela, Mesci, Pinar, Momper, Jeremiah D, Montefusco, Sandro, Moore, Spencer M, Muotri, Alysson R, Pinto, Antonella, Rosenberg, Scott C, Russo, Fabiele B, Saghatelian, Alan, Sheets, Nicholas, Shiryaev, Sergey A, Shresta, Sujan, Siqueira-Neto, Jair L, Suarez, Nicole A, Tejwani, Leon, Terskikh, Alexey V   +23 more
core   +2 more sources

In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy [PDF]

, 2020
Rationale: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the
Hu, Q, Ke, X, Li, P, Liu, Y, Luo, D, Miao, Y, Sun, J, Tan, Z, Wang, H, Wang, T, Xu, F, Zhang, Y, Zheng, Z   +12 more
core   +1 more source

The Complement System in Flavivirus Infections [PDF]

Frontiers in Microbiology, 2017
The incidence of flavivirus infections has increased dramatically in recent decades in tropical and sub-tropical climates worldwide, affecting hundreds of millions of people each year. The Flaviviridae family includes dengue, West Nile, Zika, Japanese encephalitis, and yellow fever viruses that are typically transmitted by mosquitoes or ticks, and ...
Emiliana M. Silva, Angela Silva Barbosa, Ronaldo Mohana-Borges, Jonas N. Conde   +3 more
openaire   +2 more sources

Ocular Manifestations of Flavivirus Infections

Pathogens, 2023
Flaviviruses are a group of positive sense single-stranded RNA viruses predominantly transmitted by arthropods (mainly mos-quitoes), that cause severe endemic infections and epidemics on a global scale. It represents a major cause of systemic morbidity and death that are expanding worldwide. Among this group, Dengue fever, West Nile virus, Yellow Fever,
Sourour Meziou Zina, Gautier Hoarau, Marc Labetoulle, Moncef Khairallah, Antoine Rousseau   +4 more
openaire   +3 more sources

Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells

Frontiers in Immunology, 2019
Most of the world is at risk of being infected with a flavivirus such as dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus, significantly impacting millions of lives. Importantly,
Mariah Hassert, James D. Brien, Amelia K. Pinto   +2 more
doaj   +1 more source