Results 51 to 60 of about 60,474 (247)

Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells

Frontiers in Immunology, 2019
Most of the world is at risk of being infected with a flavivirus such as dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus, significantly impacting millions of lives. Importantly,
Mariah Hassert, James D. Brien, Amelia K. Pinto   +2 more
doaj   +1 more source

In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination. [PDF]

PLoS Neglected Tropical Diseases, 2017
Infection caused by the four serotypes of dengue virus (DENV-1-4) is a leading cause of mosquito-borne disease. Clinically-severe dengue disease is more common when secondary dengue infection occurs following prior infection with a heterologous dengue ...
Stephen S Whitehead, Anna P Durbin, Kristen K Pierce, Dan Elwood, Benjamin D McElvany, Ellen A Fraser, Marya P Carmolli, Cecilia M Tibery, Noreen A Hynes, Matthew Jo, Janece M Lovchik, Catherine J Larsson, Elena A Doty, Dorothy M Dickson, Catherine J Luke, Kanta Subbarao, Sean A Diehl, Beth D Kirkpatrick   +17 more
doaj   +1 more source

Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines

Frontiers in Immunology, 2022
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan, Yuhong Pan, Yuhong Pan, Wenjun Cai, Wenjun Cai, Wenjun Cai, Anchun Cheng, Anchun Cheng, Anchun Cheng, Mingshu Wang, Mingshu Wang, Mingshu Wang, Zhongqiong Yin, Renyong Jia, Renyong Jia, Renyong Jia   +15 more
doaj   +1 more source

A glance at subgenomic flavivirus RNAs and microRNAs in flavivirus infections [PDF]

Virology Journal, 2016
The family Flaviviridae comprises a wide variety of viruses that are distributed worldwide, some of which are associated with high rates of morbidity and mortality. There are neither vaccines nor antivirals for most flavivirus infections, reinforcing the importance of research on different aspects of the viral life cycle.
Bavia, Lorena, Mosimann, Ana Luiza Pamplona, Aoki, Mateus Nóbrega, Duarte dos Santos, Claudia Nunes   +3 more
openaire   +2 more sources

Detection of novel insect flavivirus sequences integrated in Aedes albopictus (Diptera: Culicidae) in Northern Italy

Virology Journal, 2009
The presence of DNA sequences integrated from a new flavivirus related to Cell Fusing Agent and Kamiti River Virus was identified in wild Aedes albopictus mosquito populations from the provinces of Trentino and Padova, Northern Italy.
Tenorio Antonio, Seco Mari, Vázquez Ana, Roiz David, Rizzoli Annapaola   +4 more
doaj   +1 more source

A Perspective on Current Flavivirus Vaccine Development: A Brief Review

Viruses, 2023
The flavivirus genus contains several clinically important pathogens that account for tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can cause severe and potentially fatal diseases ranging from hemorrhagic fevers ...
Sudip Kumar Dutta, Thomas Langenburg
doaj   +1 more source

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Improved reference genome of the arboviral vector Aedes albopictus [PDF]

, 2020
Background: The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. With limited antiviral drugs and vaccines available, vector control is the primary approach to prevent mosquito ...
Akbari, Omar,, Antoshechkin, Igor, Biedler, James,, Bonizzoni, Mariangela, Caccone, Adalgisa, Cosme, Luciano,, Crawford, Jacob,, Failloux, Anna-Bella, Gamez, Stephanie, Ghurye, Jay, Halbach, Rebecca, Jenrette, Jeremy, Johnston, J. Spencer, Karagodin, Dmitry,, Koren, Sergey, Krsticevic, Flavia, Marconcini, Michele, Masri, Reem,, Masterson, Patrick, Miesen, Pascal, Palatini, Umberto, Papathanos, Philippos,, Phillippy, Adam,, Pischedda, Elisa, Powell, Jeffrey, Rhie, Arang, Sharakhova, Maria,, Sharma, Atashi, Thibaud-Nissen, Francoise, Tu, Zhijian, van Rij, Ronald,   +30 more
core   +5 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Flavivirus RNA in Phlebotomine Sandflies [PDF]

Vector-Borne and Zoonotic Diseases, 2010
Sandfly-transmitted phleboviruses, such as Toscana, sandfly fever Sicilian, and sandfly fever Naples, can cause human disease and circulate at high rates in Mediterranean countries. Previous studies have also established that viruses other than phleboviruses may be detected in and isolated from sand flies. The recent detection and isolation (in a large
/Moureau, Grégory, Ninove, L., Izri, A., Cook, S., de Lamballerie, Xavier, Charrel, R.   +5 more
openaire   +3 more sources