Suppression of Type I Interferon Signaling by Flavivirus NS5. [PDF]
Type I interferon (IFN-I) is the first line of mammalian host defense against viral infection. To counteract this, the flaviviruses, like other viruses, have encoded a variety of antagonists, and use a multi-layered molecular defense strategy to ...
Hai, Rong +3 more
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Simultaneous detection and differentiation of dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus by a combined reverse-transcription loop-mediated isothermal amplification assay [PDF]
Background Rapid identification and differentiation of mosquito-transmitted flaviviruses in acute-phase sera of patients and field-caught vector mosquitoes are important for the prediction and prevention of large-scale epidemics.
Shuhua Li +10 more
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Dolphin Morbillivirus in Eurasian Otters, Italy [PDF]
We report biomolecular evidence of dolphin morbillivirus in 4 wild Eurasian otters (Lutra lutra) from southern Italy; 2 animals showed simultaneous immunohistochemical reactivity against morbilliviral antigen.
Cafiero, Maria Assunta +13 more
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Flaviviruses at the territory of Serbia – present situation and challenges
The aim of this study is to summarize the data on the occurrence, presence and prevalence of some zoonotic flaviviruses, which have been actively circulating in the territory of the Republic of Serbia during past decade.
Tamaš Petrović +16 more
doaj +1 more source
Biosafety Concerns Involving Genetically Modified Mosquitoes to Combat Malaria and Dengue in Developing Countries [PDF]
Malaria and dengue are the most prevalent mosquito-borne infections worldwide. Because traditional vector control methods have proven to be insufficient to control mosquito populations in endemic areas, scientists are actively working in the design of ...
Gostin, Lawrence O., Ostera, Graciela R.
core +2 more sources
Recent Advances in Zika Virus Vaccines
The recent outbreaks of Zika virus (ZIKV) infections and associated microcephaly in newborns has resulted in an unprecedented effort by researchers to target this virus.
Himanshu Garg +2 more
doaj +1 more source
Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen [PDF]
International audienceBACKGROUND: The genus Flavivirus encompasses more than 50 distinct species of arthropod-borne viruses, including several major human pathogens, such as West Nile virus, yellow fever virus, Japanese encephalitis virus and the four ...
Marc Le Breton +9 more
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Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made ...
Michela Mazzon +17 more
doaj +1 more source
Chemokine receptors as important regulators of pathogenesis during arboviral encephalitis
The central nervous system (CNS) is a highly complex network comprised of long-lived neurons and glial cells. Accordingly, numerous mechanisms have evolved to tightly regulate the initiation of inflammatory responses within the brain.
Daniela eMichlmayr, Jean K Lim
doaj +1 more source
Genetic Resistance to Flaviviruses [PDF]
I was a graduate student in the Department of Microbiology at the University of Pennsylvania in the late 1960s and chose to do my dissertation research with Hilary Koprowski at The Wistar Institute, even though I was warned that this might not be the best training situation for me.
openaire +2 more sources

