Results 101 to 110 of about 26,407 (220)
ChemMedChem, Volume 21, Issue 16, 27 August 2026.Ligand‐based virtual screening of over five million compounds identifies a thienopyrimidinone hit as a novel allosteric nSMase2 modulator. Structure‐guided optimisation improves inhibitory potency and delivers derivatives with antiviral activity against West Nile virus, expanding the chemical space of nSMase2 inhibitors and supporting host‐directed ...
Hadrián Álvarez‐Fernández +6 more
wiley +1 more source
Protective to a T: The Role of T Cells during Zika Virus Infection
Cells, 2019 CD4 and CD8 T cells are an important part of the host’s capacity to defend itself against viral infections. During flavivirus infections, T cells have been implicated in both protective and pathogenic responses.
Ryan D. Pardy, Martin J. Richer
doaj +1 more source
Development of Antibody Therapeutics against Flaviviruses
, 2017 Recent outbreaks of Zika virus (ZIKV) highlight the urgent need to develop efficacious interventions against flaviviruses, many of which cause devastating epidemics around the world. Monoclonal antibodies (mAb) have been at the forefront of treatment for
Haiyan Sun, Huafang Lai, Qiang Chen
core +1 more source
Dead Crow Density and West Nile Virus Monitoring, New York
Emerging Infectious Diseases, 2005 New York State used the health commerce system to monitor the number of West Nile virus (WNV) human disease cases and the density of dead crows. In each year from 2001 to 2003 and for the 3 years combined, persons living in New York counties (excluding ...
Millicent Eidson +6 more
doaj +1 more source
Construction of Stable Reporter Flaviviruses and Their Applications
, 2020 Flaviviruses are significant human pathogens that cause frequent emerging and reemerging epidemics around the world. Better molecular tools for studying, diagnosing, and treating these diseases are needed.
Coleman Baker, Pei-Yong Shi
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Antigenic relationship among zoonotic flaviviruses from Italy [PDF]
, 2019 Here we report studies of the antigenic relationship of West Nile virus (WNV) and Usutu virus (USUV), two zoonotic flaviviruses from Italy, together with a Japanese encephalitis virus (JEV) strain and compared them with their genetic relationship using ...
Ronchi, Gaetano Federico +14 more
core +1 more source
, 2017 Distribution of PRNT90 titers for 7 flaviviruses among 30 black howlers positive for several flaviviruses without four-fold differences (undetermined flavivirus).
Martín M. Kowalewski (3740704) +7 more
core +1 more source
Flaviviruses at the territory of Serbia – present situation and challenges
Archives of Veterinary Medicine, 2019 The aim of this study is to summarize the data on the occurrence, presence and prevalence of some zoonotic flaviviruses, which have been actively circulating in the territory of the Republic of Serbia during past decade.
Tamaš Petrović +16 more
doaj +1 more source
Recent Advances in Zika Virus Vaccines
Viruses, 2018 The recent outbreaks of Zika virus (ZIKV) infections and associated microcephaly in newborns has resulted in an unprecedented effort by researchers to target this virus.
Himanshu Garg +2 more
doaj +1 more source
Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
Viruses, 2019 Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made ...
Michela Mazzon +17 more
doaj +1 more source