Results 111 to 120 of about 479,337 (405)
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
Advanced Science, EarlyView.This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan +12 more
wiley +1 more source
Impact of different solvents on the recovery of bioactive compounds and antioxidant properties from lemon (Citrus limon L.) pomace waste [PDF]
, 2016 The effects of different solvents on the recovery of (i) extractable solids (ES), (ii) total phenolic compounds (TPC), (iii) total flavonoid content (TFC), (iv) vitamin C, and (v) antioxidant activity from lemon pomace waste were investigated.
Bowyer, Michael C. +6 more
core +2 more sources
Flavonoid Functions in Plants and Their Interactions with Other Organisms
Plants, 2018 Flavonoids are structurally diverse secondary metabolites in plants, with a multitude of functions. These span from functions in regulating plant development, pigmentation, and UV protection, to an array of roles in defence and signalling between plants ...
U. Mathesius
semanticscholar +1 more source
Direct Quantification of Protein–Protein Interactions in Living Bacterial Cells
Advanced Science, EarlyView.Quantitative measurement of protein–protein interactions in living cells is vital for biotechnology applications. Fluorescence resonance energy transfer (FRET) signals in bacterial cells are often weak, leading to false‐positive. Quantitative FRET measurements are implemented to overcome the weak FRET signal.
Soojung Yi +12 more
wiley +1 more source
In vitro ion chelating, antioxidative mechanism of extracts from fruits and barks of tetrapleura tetraptera and their protective effects against fenton mediated toxicity of metal ions on liver homogenates [PDF]
, 2015 The aim of the present study was to investigate the antioxidant activity and protective potential of T. tetraptera extracts against ion toxicity. The antioxidant activity of the extracts was investigated spectrophotometrically against several radicals (1,
Biapa, P. C. N. +6 more
core +3 more sources
Sains Medika, 2016 Aging is inevitable process, however human comes into aging is in difference way and difference rates. Some of them undergo aging earlier due to degenerative diseases, unable to reach the maximum lifespan and are thus denominated secondary aging (Huebschmann AG, 2011).
openaire +4 more sources
Antiviral activities of flavonoids
Biomedicine & Pharmacotherapy, 2021 Flavonoids are natural phytochemicals known for their antiviral activity. The flavonoids acts at different stages of viral infection, such as viral entrance, replication and translation of proteins. Viruses cause various diseases such as SARS, Hepatitis, AIDS, Flu, Herpes, etc.
Badshah, Syed Lal +5 more
openaire +3 more sources
Frontiers in Plant Science, 2019 Flavonoids are a class of plant specialized metabolites with more than 6,900 known structures and play important roles in plant survival and reproduction.
T. Nakayama +2 more
semanticscholar +1 more source
Advanced Science, EarlyView.Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang +10 more
wiley +1 more source
Frontiers in Nutrition, 2022 BackgroundMetabolic associated fatty liver disease (MAFLD) formerly known as non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease.
Junlu Tong +6 more
doaj +1 more source