Results 121 to 130 of about 612,247 (342)

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Optimization of the Enzyme-assisted Extraction and Tyrosinase Inhibition of the Flavonoids from Thinned Fruits of Guanxi Pummelo (Citrus grandis (L.) Osbeck)

Shipin gongye ke-ji
The aim of this paper was to explore the process of β-glucosidase-assisted extraction of flavonoids from thinned fruits of Guanxi pummelo and the inhibitory effect of the extracted flavonoids on tyrosinase.
Shu'an HUANG, Hongxia DING, Yuanfan YANG, Hui NI   +3 more
doaj   +1 more source

Effect of Processing Methods on Nutritive and Antinutritive Properties of Seeds of Brachystegia eurycoma and Detarium microcarpum from Nigeria [PDF]

, 2009
Proximate analysis of the seeds of Brachystegia eurycoma and Detrarium microcarpum were carried out on both the dehulled and undehulled samples of the flour.
Iweala, E. E. J., Kanu, Ijeoma, Onwuchekwa, C. C., Uhuegbu, F. O.   +3 more
core   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by B-glucuronidase from Neutrophils [PDF]

, 2010
Flavonoids are inactivated by phase II metabolism and occur in the body as glucuronides. Mammalian ß-glucuronidase released from neutrophils at inflammatory sites may be able to deconjugate and thus activate flavonoid glucuronides.
Arts, I.C.W., Bartholomé, R., Bast, A., Dagnelie, P.C., Haenen, G., Hollman, P.C.H., Keijer, J., Kroon, P.A., Needs, P.W., Roos, D.   +9 more
core   +2 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Extraction, Component Analysis and Biological Activity Evaluation of Total Flavonoids from Phellinus igniarius

Shipin gongye ke-ji
In order to study the extraction technology of total flavonoids from Phellinus igniarius systematically, clarify the composition and content of flavonoids in total flavonoids, and explore the biological activity of total flavonoids from Phellinus ...
Tingwei FU, Ziwei ZHOU, Ying SHAO, Peng ZHANG, Xiaoya NING, Yang YANG, Anhui CHEN   +6 more
doaj   +1 more source

The leaves of Mediterranean mandarin could be used as an important source of hesperidin, nobiletin and tangeretin. : S20P04 [PDF]

, 2012
Citrus are rich in flavonoids such as flavones and flavanones. Recent studies have shown that these phytonutrients play a beneficial role for human health.
Bidel, Luc P.R., Durand, Marie V.S, Fanciullino, Anne Laure, Froelicher, Yann, Jay-Allemand, Christian, Ollitrault, Patrick   +5 more
core  

Betalains and phenolic compounds of leaves and stems of Alternanthera brasiliana and Alternanthera tenella [PDF]

, 2018
Betacyanins and phenolic compounds from acetonitrile:acidified water extracts of Alternanthera brasiliana and Alternanthera tenella were characterized and quantified using a high-performance liquid chromatography system coupled with diode array and ...
Alvarez, I., De Ancos, B., Deladino, Lorena, Molina García, A. D., Schneider Teixeira, Aline, Sánchez Moreno, C.   +5 more
core   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

Advanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao, Hongli Zhang, Yating Yang, Wei‐Dong Chen, Yan‐Dong Wang   +4 more
wiley   +1 more source