Results 81 to 90 of about 198,497 (264)

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis

Animal Models and Experimental Medicine, EarlyView.
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu, Jie Mo, Cheng Liang, Qingting Chen, Bin Yang, Jiaqi Liu   +5 more
wiley   +1 more source

Radix Ilicis Pubescentis total flavonoids ameliorates neuronal damage and reduces lesion extent in a mouse model of transient ischemic attack

Neural Regeneration Research, 2016
Flavonoids are a major component in the traditional Chinese medicine Radix Ilicis Pubescentis. Previous studies have shown that the administration of Radix Ilicis Pubescentis total flavonoids is protective in cerebral ischemia. However, to our knowledge,
Ming-san Miao, Lin Guo, Rui-qi Li, Xiao-lei Zhang   +3 more
doaj   +1 more source

New progress in the extraction and identification of Mexican cochineal (Dactylopius coccus) in fresh dyed wool and dyed wool with artificially accelerated aging and color description

Color Research &Application, Volume 48, Issue 1, Page 151-164, January/February 2023., 2023
Abstract The main purpose of this study was to determine if a method developed in the laboratory by HPLC‐ESI‐QToF was able to identify the characteristic compounds of the Mexican cochineal (Dactylopius coccus) in freshly dyed wool fiber and following an artificially accelerated aging process.
Karen Cruz Mojica, Mayra León Santiago, Emiliano Varela García, Marisol Reyes Lezama, Everardo Tapia Mendoza   +4 more
wiley   +1 more source

Flavonoid‐Derived Probes for the Detection of Islet Amyloid Polypeptide Aggregates

Analysis &Sensing, EarlyView.
Misfolding and aggregation of islet amyloid polypeptide (IAPP) has been implicated in Type‐2 diabetes (T2D), contributing to β‐cell dysfunction. We developed flavonoid‐based probes, F4 and MF1, for detecting IAPP fibrils. These probes showed improved fluorescence response, over 10‐fold higher binding affinity than Thioflavin T and enabled specific ...
Zijie Luo, Yijia Xu, Jiayi Fan, Isabel E. Lean, Thomas P. Davis, Ibrahim Javed, Amandeep Kaur   +6 more
wiley   +1 more source

Integrated impact of environmentally friendly extraction and recovery methods on almond oil quality: Insights from a lipidomic perspective

Journal of the American Oil Chemists' Society, EarlyView.
Abstract Although aqueous and enzymatic extractions are solvent‐free alternatives for extracting oil and proteins from almond flour, most of the extracted oil becomes entrapped in an emulsion and needs demulsification for recovery. To assess how extraction and demulsification methods impact yields and quality, a lipidomic approach was used to ...
Fernanda Furlan Goncalves Dias, Bianca Ferraz Teixeira, Ameer Y. Taha, Juliana Maria Leite Nobrega de Moura Bell   +3 more
wiley   +1 more source

Flavonoids as receptor tyrosine kinase inhibitors in lung cancer

Journal of Functional Foods, 2023
Flavonoids are polyphenolic compounds with promising anti-cancer properties, as well as low toxicity and high potency. Based on recent research, a potential mechanism of flavonoids appear to be via receptor tyrosine kinase (RTK) inhibition.
Sareshma Sudhesh Dev, Reyhaneh Farghadani, Syafiq Asnawi Zainal Abidin, Iekhsan Othman, Rakesh Naidu   +4 more
doaj  

Calotropis procera Latex Extract as an Effective Green Corrosion Inhibitor for Mild Steel in Acidic Medium: Experimental and Quantum Chemical Approaches

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In this work, Calotropis procera latex extract (CPLE) was evaluated as an environmentally benign corrosion inhibition on mild steel in 1‐M HCl using gravimetric, electrochemical, surface, and computational approaches. The results revealed that CPLE exhibited an efficient corrosion inhibitor with the efficiency of 94.26% and 93.10% at 200‐ppm ...
M. Salman, Z. Zondi, M. E. Mashuga, I. Bahadur, S. Kumar, J. Haque, S. K. Pandey, F. Mohammad, A. El‐khlifi   +8 more
wiley   +1 more source

Comparative evaluation of the postbleaching application of sodium ascorbate, alpha‐tocopherol, and quercetin on shear bond strength of composite resin to enamel

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1598-1604, December 2022., 2022
Abstract Objective This study aimed to evaluate and compare the impacts of the postbleaching application of sodium ascorbate, alpha‐tocopherol, and quercetin on the shear bond strength (SBS) of composite resin. Material and Methods 60 extracted intact maxillary first premolars were collected and were randomly divided into five experimental groups as ...
Marzieh Moradian, Maryam Saadat, Mohammad Hossein S. Shiri, Fatemeh Sohrabniya   +3 more
wiley   +1 more source

Extraction Process Optimization and Antioxidant, Anti-Inflammatory Activity of Total Flavonoids from Aletris spicata (Thunb.) Franch.

Shipin gongye ke-ji
The objective of this study was to optimize the extraction process of total flavonoids from Aletris spicata (Thunb.) Franch. and explore its antioxidant, anti-inflammatory activity. With the yield of total flavonoids as an evaluation index, single factor
Jing YANG, Dingding LIU, Teng CHEN, Jing LIU, Xiuping MA, Zuhua WANG   +5 more
doaj   +1 more source