Results 41 to 50 of about 44,095 (208)

Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site [PDF]

, 2002
The quinol-fumarate reductase (QFR) respiratory complex of Escherichia coli is a four-subunit integral-membrane complex that catalyzes the final step of anaerobic respiration when fumarate is the terminal electron acceptor.
Cecchini, Gary, Croal, Laura R., Iverson, Tina M., Luna-Chavez, César, Rees, Douglas C.   +4 more
core   +1 more source

Comparative transcriptomic analysis unveils interactions between the regulatory CarS protein and light response in Fusarium [PDF]

, 2019
Background The orange pigmentation of the agar cultures of many Fusarium species is due to the production of carotenoids, terpenoid pigments whose synthesis is stimulated by light.
Limón Mirón, María del Carmen, Pardo Medina, Javier, Parra Rivero, Obdulia, Romero Campero, Francisco José, Ruger Herreros, María Macarena, Ávalos Cordero, Francisco Javier   +5 more
core   +1 more source

Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy

Neurobiology of Disease, 2018
Myotonic dystrophy (DM) is a progressive, multisystem disorder affecting skeletal muscle, heart, and central nervous system. In both DM1 and DM2, microsatellite expansions of CUG and CCUG RNA repeats, respectively, accumulate and disrupt functions of ...
Gang Chen, Russell E. Carter, John D. Cleary, Tammy S. Reid, Laura P. Ranum, Maurice S. Swanson, Timothy J. Ebner   +6 more
doaj   +1 more source

Distribution in Different Organisms of Amino Acid Oxidases with FAD or a Quinone As Cofactor and Their Role as Antimicrobial Proteins in Marine Bacteria

Marine Drugs, 2015
Amino acid oxidases (AAOs) catalyze the oxidative deamination of amino acids releasing ammonium and hydrogen peroxide. Several kinds of these enzymes have been reported.
Jonatan C. Campillo-Brocal, Patricia Lucas-Elío, Antonio Sanchez-Amat   +2 more
doaj   +1 more source

Assigning function to active site residues of Schistosoma mansoni thioredoxin/glutathione reductase from analysis of transient state reductive half-reactions with variant forms of the enzyme

Frontiers in Molecular Biosciences, 2023
Thioredoxin/glutathione reductase (TGR) from the platyhelminthic parasitic worms has recently been identified as a drug target for the treatment of schistosomiasis.
Madison M. Smith, Graham R. Moran
doaj   +1 more source

Genome Sequence of Stenotrophomonas maltophilia PML168, Which Displays Baeyer-Villiger Monooxygenase Activity [PDF]

, 2012
Stenotrophomonas maltophilia PML168 was isolated from Wembury Beach on the English Coast from a rock pool following growth and selection on agar plates.
Baeyer, C. Bradley, C. N. Jensen, Fraaije, G. Grogan, Hauben, J. Nissimov, Jensen, Joint, K. Gharbi, K. Mavromatis, K. Tait, K. Weynberg, Lai, M. J. Allen, M. Muhling, Markowitz, Rao, Reid, S. T. Ali, U. Trivedi, van Berkel, Willetts, Zerbino   +23 more
core   +1 more source

Archaeal LOV domains from Lake Diamante: first functional characterization of a halo-adapted photoreceptor

Frontiers in Microbiology
High-altitude Andean lakes (HAALs) represent polyextreme environments where diverse photoinduced processes have been documented. In this study, we investigated Light-Oxygen-Voltage (LOV) photoreceptors and identified 28 archaeal sequences from Lake ...
Lorena Valle, Lorena Valle, Yonathan J. Coronel, Yonathan J. Coronel, Guillermina E. Bravo, Joaquín A. Díaz, Virginia Helena Albarracín, Virginia Helena Albarracín, María E. Farías, Inés Abatedaga   +9 more
doaj   +1 more source

VpStyA1/VpStyA2B of Variovorax paradoxus EPS: An Aryl Alkyl Sulfoxidase Rather than a Styrene Epoxidizing Monooxygenase

Molecules, 2018
Herein we describe the first representative of an E2-type two-component styrene monooxygenase of proteobacteria. It comprises a single epoxidase protein (VpStyA1) and a two domain protein (VpStyA2B) harboring an epoxidase (A2) and a FAD-reductase (B ...
Dirk Tischler, Ringo Schwabe, Lucas Siegel, Kristin Joffroy, Stefan R. Kaschabek, Anika Scholtissek, Thomas Heine   +6 more
doaj   +1 more source

KillerRed protein based in vivo photodynamic therapy and corresponding tumor metabolic imaging [PDF]

Journal of Innovative Optical Health Sciences, 2016
Photodynamic therapy (PDT) gains wide attention as a useful therapeutic method for cancer. It is mediated by the oxygen and photosensitizer under the specific light irradiation to produce the reactive oxygen species (ROS), which induce cellular toxicity ...
Qiaoya Lin, Shuang Sha, Fei Yang, Honglin Jin, Zhihong Zhang   +4 more
doaj   +1 more source

Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity [PDF]

, 2011
The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) enhances oxidative metabolism in skeletal muscle. Excessive lipid oxidation and electron transport chain activity can, however, lead to the accumulation of harmful metabolites and ...
Handschin, C., Santos, G., Summermatter, S., Troxler, H.   +3 more
core   +1 more source