Results 21 to 30 of about 11,677 (208)
Assays of D-Amino Acid Oxidase Activity
D-amino acid oxidase (DAAO) is a well-known flavoenzyme that catalyzes the oxidative FAD-dependent deamination of D-amino acids. As a result of the absolute stereoselectivity and broad substrate specificity, microbial DAAOs have been employed as ...
Elena Rosini +5 more
doaj +1 more source
Enzymatic functionalization of carbon-hydrogen bonds [PDF]
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H. +2 more
core +1 more source
Comparative genome analyses have led to the discovery and characterization of novel flavin- and folate-dependent methyltransferases that mainly function in DNA precursor synthesis and post-transcriptional RNA modification by forming (ribo) thymidylate ...
Hannu Myllykallio +4 more
doaj +1 more source
Alpha- and beta-adrenergic mediation of changes in metabolism and Na/K exchange in rat brown fat [PDF]
Double- and triple-barreled ion-sensitive microelectrodes were used to measure changes in extracellular K+ and Na+ concentrations ([K+]o, [Na+]o) in brown fat.
Coles, Jonathan A. +2 more
core +2 more sources
Flavoproteins often employ radical mechanisms in their enzymatic reactions. This involves paramagnetic species, which can ideally be investigated with electron paramagnetic resonance (EPR) spectroscopy. In this chapter we focus on the example of flavin-based photoreceptors and discuss, how different EPR methods have been used to extract information ...
Brosi, Richard +2 more
openaire +2 more sources
Organohalide respiration (OHR) is the energy metabolism of anaerobic bacteria able to use halogenated organic compounds as terminal electron acceptors.
Géraldine F. Buttet +4 more
doaj +1 more source
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). The binding of the FAD and/or FMN cofactors to flavoproteins is critical for regulating their assembly ...
Chiara Murgia +2 more
doaj +1 more source
The multifunctional nature of human flavoproteins is critically linked to their ability to populate multiple conformational states. Ligand binding, post-translational modifications and disease-associated mutations can reshape this functional landscape ...
Juan Luis Pacheco-Garcia +10 more
doaj +1 more source
Surface Fluorescence Studies of Tissue Mitochondrial Redox State in Isolated Perfused Rat Lungs [PDF]
We designed a fiber-optic-based optoelectronic fluorometer to measure emitted fluorescence from the auto-fluorescent electron carriers NADH and FAD of the mitochondrial electron transport chain (ETC).
Audi, Said H. +4 more
core +2 more sources
Evolution of function in the "two dinucleotide binding domains" flavoproteins. [PDF]
Structural and biochemical constraints force some segments of proteins to evolve more slowly than others, often allowing identification of conserved structural or sequence motifs that can be associated with substrate binding properties, chemical ...
Sunil Ojha +2 more
doaj +1 more source

