Results 21 to 30 of about 11,677 (208)

Assays of D-Amino Acid Oxidase Activity

open access: yesFrontiers in Molecular Biosciences, 2018
D-amino acid oxidase (DAAO) is a well-known flavoenzyme that catalyzes the oxidative FAD-dependent deamination of D-amino acids. As a result of the absolute stereoselectivity and broad substrate specificity, microbial DAAOs have been employed as ...
Elena Rosini   +5 more
doaj   +1 more source

Enzymatic functionalization of carbon-hydrogen bonds [PDF]

open access: yes, 2011
The development of new catalytic methods to functionalize carbon–hydrogen (C–H) bonds continues to progress at a rapid pace due to the significant economic and environmental benefits of these transformations over traditional synthetic methods.
Arnold, Frances H.   +2 more
core   +1 more source

Unique Features and Anti-microbial Targeting of Folate- and Flavin-Dependent Methyltransferases Required for Accurate Maintenance of Genetic Information

open access: yesFrontiers in Microbiology, 2018
Comparative genome analyses have led to the discovery and characterization of novel flavin- and folate-dependent methyltransferases that mainly function in DNA precursor synthesis and post-transcriptional RNA modification by forming (ribo) thymidylate ...
Hannu Myllykallio   +4 more
doaj   +1 more source

Alpha- and beta-adrenergic mediation of changes in metabolism and Na/K exchange in rat brown fat [PDF]

open access: yes, 1985
Double- and triple-barreled ion-sensitive microelectrodes were used to measure changes in extracellular K+ and Na+ concentrations ([K+]o, [Na+]o) in brown fat.
Coles, Jonathan A.   +2 more
core   +2 more sources

EPR on Flavoproteins [PDF]

open access: yes, 2014
Flavoproteins often employ radical mechanisms in their enzymatic reactions. This involves paramagnetic species, which can ideally be investigated with electron paramagnetic resonance (EPR) spectroscopy. In this chapter we focus on the example of flavin-based photoreceptors and discuss, how different EPR methods have been used to extract information ...
Brosi, Richard   +2 more
openaire   +2 more sources

The Membrane-Bound C Subunit of Reductive Dehalogenases: Topology Analysis and Reconstitution of the FMN-Binding Domain of PceC

open access: yesFrontiers in Microbiology, 2018
Organohalide respiration (OHR) is the energy metabolism of anaerobic bacteria able to use halogenated organic compounds as terminal electron acceptors.
Géraldine F. Buttet   +4 more
doaj   +1 more source

New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases

open access: yesNutrition & Metabolism, 2023
Riboflavin, or vitamin B2, is an essential nutrient that serves as a precursor to flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). The binding of the FAD and/or FMN cofactors to flavoproteins is critical for regulating their assembly ...
Chiara Murgia   +2 more
doaj   +1 more source

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

open access: yesRedox Biology, 2021
The multifunctional nature of human flavoproteins is critically linked to their ability to populate multiple conformational states. Ligand binding, post-translational modifications and disease-associated mutations can reshape this functional landscape ...
Juan Luis Pacheco-Garcia   +10 more
doaj   +1 more source

Surface Fluorescence Studies of Tissue Mitochondrial Redox State in Isolated Perfused Rat Lungs [PDF]

open access: yes, 2012
We designed a fiber-optic-based optoelectronic fluorometer to measure emitted fluorescence from the auto-fluorescent electron carriers NADH and FAD of the mitochondrial electron transport chain (ETC).
Audi, Said H.   +4 more
core   +2 more sources

Evolution of function in the "two dinucleotide binding domains" flavoproteins. [PDF]

open access: yesPLoS Computational Biology, 2007
Structural and biochemical constraints force some segments of proteins to evolve more slowly than others, often allowing identification of conserved structural or sequence motifs that can be associated with substrate binding properties, chemical ...
Sunil Ojha   +2 more
doaj   +1 more source

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