Results 71 to 80 of about 9,572 (201)

Flecainide overdose – support using an intra-aortic balloon pump

BMC Emergency Medicine, 2005
Background Flecainide is an antiarrhythmic agent which is being used increasingly for the management of super-ventricular arrhythmias. Overdose with flecainide is frequently fatal with mortality reported as high as 22% due to arrhythmias, myocardial ...
Brown Peter D, Mitchell Andrew RJ, Timperley Jonathan, West Nicholas EJ   +3 more
doaj   +1 more source

Comparison of the effects of antiarrhythmic drugs flecainide and verapamil on fKv1.4ΔN channel currents in Xenopus oocytes [PDF]

, 2012
Hui Chen, Dong Zhang, Sheng-ping Chao, Jiang-hua Ren, Lin Xu, Xuejun Jiang, Shimin Wang   +6 more
openalex   +1 more source

Acute Management of Paroxysmal Atrial Fibrillation with Intravenous Flecainide plus Oral Beta-Blockers

International Journal of Translational Medicine
Background: Intravenous (IV) flecainide is recommended for the pharmacological cardioversion of recent-onset atrial fibrillation (AF). The aim of this study was to study the efficacy and safety of IV flecainide, co-administered with oral b-blockers, for ...
Athanasios Kartalis, Dimitrios Afendoulis, Petros Voutas, Maria Moutafi, Nikolaos Papagiannis, Stefanos Garoufalis, Nikolaos Kartalis, Nikolaos Smyrnioudis, Antonios Ziakas, Matthaios Didagelos   +9 more
doaj   +1 more source

The use of flecainide in critical neonates and infants with incessant supraventricular tachycardias

Türk Kardiyoloji Derneği Arşivi, 2015
OBJECTIVE: This study aimed to evaluate the efficacy of flecainide therapy in neonates and infants with drug resistant incessant supraventricular tachycardia.
Yakup Ergul, Isa Ozyilmaz, Murat Saygi, Hasan Tahsin Tola, Celal Akdeniz, Volkan Tuzcu   +5 more
doaj   +1 more source

Delayed diagnosis of Brugada syndrome in a patient with aborted sudden cardiac death and initial negative flecainide challenge

Clinical Case Reports, 2017
Key Clinical Message A negative flecainide challenge does not rule out Brugada syndrome even in the presence of nonfatal cardiac arrest as the first manifestation of the disease.
Samuel Chauveau, Olivier Le Vavasseur, Philippe Chevalier   +2 more
doaj   +1 more source

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model

Frontiers in Pharmacology, 2019
The cardiac Nav1.5 mediated sodium current (INa) generates the upstroke of the action potential in atrial and ventricular myocytes. Drugs that modulate this current can therefore be antiarrhythmic or proarrhythmic, which requires preclinical evaluation ...
Dieter V. Van de Sande, Ivan Kopljar, Ivan Kopljar, Ard Teisman, David J. Gallacher, Dirk J. Snyders, Hua Rong Lu, Alain J. Labro   +7 more
doaj   +1 more source

Flecainide challenge test for the diagnosis of Brugada syndrome [PDF]

, 2004
Mukesh Kumar Sinha, Debankini Dasgupta, J P Lyons   +2 more
openalex   +1 more source

Low RyR2 Sensitivity to Flecainide Combined with Slow Sarcolemmal Entry and Rapid Mitochondrial Accumulation May Explain the Absence of RyR2 Effects Intact Wild Type Myocytes [PDF]

, 2020
Emma Jane Steer, Zhaokang Yang, Derek S. Steele   +2 more
openalex   +1 more source

Complete Heart Block Secondary to Flecainide Toxicity: Is It Time for CYP2D6 Genotype Testing? [PDF]

, 2020
Bao Hui Poh, Jan Hau Lee, Abdul Alim Abdul Haium, Tze Liang Jonathan Choo   +3 more
openalex   +1 more source

Brugada Syndrome Unmasked by Fever but not Flecainide Challenge in a Renal Transplant Patient [PDF]

, 2017
Esther Davis
openalex   +1 more source