Results 81 to 90 of about 5,317,081 (363)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

FMLA Leave Determinations/Medical Certifications [PDF]

open access: yes, 2007
Part one of this memorandum provides a summary of questions asked and comments submitted in response to the DOL request for information ( RFI ) about FMLA leave determinations and medical certifications.
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Higher Education in Information era [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2010
Introduction: The process of higher education is highly significant in any society. These days, universities have come across a main transformation. Lack of budget, an increase in the number of university students, a change in the student population, up ...
ناهید ظریف صنایعی
doaj  

Development and Optimization of 3D-Printed Flexible Electronic Coatings: A New Generation of Smart Heating Fabrics for Automobile Applications [PDF]

open access: gold, 2023
Léopold Diatezo   +5 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Resources for Workplace Flexibility, Families and Child Development [PDF]

open access: yes, 2011
A list of resources for Workplace Flexibility, Families and Child ...
Workplace Flexibility 2010, Georgetown University Law Center
core   +1 more source

Getting a Grip on Cognitive Flexibility

open access: yesCurrent Directions in Psychological Science, 2018
Cognitive flexibility refers to the ability to quickly reconfigure our mind, as when we switch between different tasks. This review highlights recent evidence showing that cognitive flexibility can be conditioned by simple incentives typically known to ...
S. Braem, T. Egner
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Preparation and Properties of Insulation Flexible Cork Composites

open access: yesCailiao gongcheng, 2017
The cork composite (RC16) is prepared by using one-component moisture curing polyurethane (U030) as cork adhesive, and the cork composite exhibits excellent mechanical properties and flexibility, and its density is 0.40g/cm3.
GUO An-ru   +3 more
doaj   +1 more source

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