Results 41 to 50 of about 70,005 (261)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Jixie qiangdu, 2020 The flexible bearing is one of the key components of wave generator（ WG） in Harmonic Drive（ HD）. Its load and life studies are key to the reliable operation of HD.
PAN XueJiao +3 more
doaj
Bearing Capacity of Unbonded Flexible Pipe Carcass with Corrosion Defects
Shiyou jixie, 2022 The innermost carcass of flexible pipe directly contacts with the transported medium,and corrosion occurs inevitably,which will affect the pressure bearing capacity of the pipeline.In order to investigate the influence of corrosion defects on the ...
Lu Zhongqi +4 more
doaj
The FEM Application in Numerical Analysis of Slewing Rings Roller/Ball Combination Bearing
Communications, 2017 Slewing bearings are selected based on the characteristics of capacity, which determine the area of the permissible load of the bearing. This capacity of a bearing does not take into account the real operating conditions of a bearing.
Marek Krynke, Piotr Sygut
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Rotor-Bearing System Stability Performance Comparing Hybrid versus Conventional Bearings
International Journal of Rotating Machinery, 2005 New closed-form expressions for calculating the linear stability thresholds for rigid and flexible Jeffcott systems and the imbalance response for a rotor supported on a hybrid bearing are presented.
Gomez-Mancilla Julio +2 more
doaj +2 more sources
An Influence Analysis of the Bearing Waviness on the Vibrations of a Flexible Gear
MachinesRoller bearing manufacturing errors have been proven to be critical factors affecting the vibrations of gear systems. Waviness is one main form of manufacturing error affecting the operational performance and life of bearings.
Shenlong Li +3 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source