Results 51 to 60 of about 14,390,409 (244)

Flexible work options within the organisational system

open access: yes, 2006
The availability of flexible work options provides an opportunity for individuals to shape their careers in order to optimise their work and life goals. This study takes a systems theory approach to examine how the use of flexible work options influences
Chee, MunLi, Albion, Majella J.
core   +1 more source

The Differentiation–Integration Paradox of Hybrid Work: A Focus Group Exploration of Team and Individual Mechanisms

open access: yesAdministrative Sciences
Despite the growing prevalence of hybrid work, our understanding of its effects on employees and teams is still restricted by ambiguous and conflicting findings.
Elena Cristina Manole   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

To what extent has the adoption of flexible mobile working transformed staff operations within Cheshire East Council ICT strategy? [PDF]

open access: yes, 2010
For many years Central Government has investigated ways in which to streamline Local Government Authorities (LGA), in order to provide better value services to its citizens.
Evans, Sarah-Jayne
core   +2 more sources

المسؤولية العقدية في عقد العمل عن بعد. [PDF]

open access: yesمجلة البحوث القانونية و الاقتصادية
هدفت هذه الدراسة إلى تحديد طبيعة المسؤولية العقدية الناشئة عن عقد العمل عن بُعد، حيث تناولت مشكلة تحديد المسؤولية المدنية العقدية التي تترتب على هذا النوع من العقود، سواء من حيث التزامات العامل أو صاحب العمل، ومدى إخلال أي منهما بهذه الالتزامات.
مهند نايف محمد الشوابكه
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

An examination of the relationship between flexible work arrangements, work-family conflict, organizational commitment, and job performance

open access: yesManagement, 2019
Many employees are often faced with an inter-role conflict between work and that of a family in the U.S. However, business leaders and Human Resource Management (HRM) may not recognize the problem affecting white-collar employees. The purpose of this non-
Ongaki Jacob
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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