Results 71 to 80 of about 5,905,568 (348)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Flexible human-robot cooperation models for assisted shop-floor tasks [PDF]
, 2017 The Industry 4.0 paradigm emphasizes the crucial benefits that collaborative robots, i.e., robots able to work alongside and together with humans, could bring to the whole production process.
Bruno, Barbara +5 more
core +2 more sources
Employee retention in the Malaysian banking industry: Do flexible practices work?
South African Journal of Business Management, 2015 The objective of the study was to determine whether employee retention in Malaysian banks can be improved through flexible working. Using a quantitative approach, the effects of five types of flexible working practice, i.e.
M. Mansor, A. ldris
doaj +1 more source
, 2020 A global response to Covid-19 pandemic has triggered issues related to stress and social restrictions;thus, mental health is seen as a particular area of concern for social well-being for both policymakers and corporate regulators/companies Given that ...
Zoe Warmate, M. Eldaly, Ahmed A. Elamer
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
International Journal of Human Resource Studies, 2019 The research focused on relationship between flexible working arrangements, work-life balance and job satisfaction in Karachi’s public universities. To investigate the null hypothesis that there is no relationship between these variables. Research design
Maha Aziz-Ur-Rehman, D. Siddiqui
semanticscholar +1 more source
Work-Life Balance and Flexible Working Arrangements in the European Union [PDF]
, 2017 [Excerpt] The reconciliation of work and life responsibilities has become an increasingly relevant policy topic in recent decades. It has an implicit societal value linked to gender equality and quality of life.
Eurofound
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Health and psychosocial effects of flexible working hours
Revista de Saúde Pública, 2004 OBJECTIVE: To examine whether any impairments in health and social lives can be found under different kinds of flexible working hours, and whether such effects are related to specific characteristics of these working hours.
Daniela Janssen, Friedhelm Nachreiner
doaj +1 more source