Results 71 to 80 of about 381,775 (307)

Swimming abilities of temperate pelagic fish larvae prove that they may control their dispersion in coastal areas [PDF]

, 2019
The Sense Acuity and Behavioral (SAAB) Hypothesis proposes that the swimming capabilities and sensorial acuity of temperate fish larvae allows them to find and swim towards coastal nursery areas, which are crucial for their recruitment. To gather further
Baptista, Vânia, Castanho, Sara, Cruz, Joana, Leitão, Francisco Miguel de Sousa, Morais, Pedro, Pousão-Ferreira, P., Ribeiro, L., Teodosio, Maria Alexandra, Wolanski, E.   +8 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Addressing sagittal plane imbalance in primary total knee arthroplasty: functional alignment outperforms kinematic and mechanical alignment techniques

Bone & Joint Open
Aims: Sagittal plane imbalance (SPI), or asymmetry between extension and flexion gaps, is an important issue in total knee arthroplasty (TKA). The purpose of this study was to compare SPI between kinematic alignment (KA), mechanical alignment (MA), and ...
Victor A. van de Graaf, Tony S. Shen, Jil A. Wood, Darren B. Chen, Samuel J. MacDessi   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Tibial insert design significantly alters knee kinematics using a single cruciate-retaining total knee implant: an in vitro study

Bone & Joint Open
Aims: Patient dissatisfaction is not uncommon following primary total knee arthroplasty. One proposed method to alleviate this is by improving knee kinematics.
Martin Faschingbauer, Jakob Hambrecht, Jonas Schwer, John R. Martin, Heiko Reichel, Andreas Seitz   +5 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: Preliminary study [PDF]

, 2012
Objective: To examine adiposity and sedentary behavior in relation to health-related quality of life (QoL) in patients with early schizophrenia. Methods: A cross-sectional study was used to assess adiposity by dual-energy X-ray absorptiometry scans ...
Brar, JS, Ganguli, R, Strassnig, M
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Incidence and mechanism of the pivot shift. An in vitro study. [PDF]

, 1999
Accepted ...
Amis, AA, Andersen, HN, Basso, O, Bull, AM, Targett, J   +4 more
core  

Galaxy-Galaxy Flexion: Weak Lensing to Second Order

, 2004
In this paper, we develop a new gravitational lensing inversion technique. While traditional approaches assume that the lensing field varies little across a galaxy image, we note that this variation in the field can give rise to a ``Flexion'' or bending ...
Bacon, David J., Goldberg, David M.
core   +1 more source