Results 211 to 220 of about 897,227 (298)

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Drone-Based Statistical Detection of Methane Anomalies Around Abandoned Oil and Gas Well Sites. [PDF]

Sensors (Basel)
Thomas WH, Wang C.
europepmc   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

AI-enabled drones for date palm pollination. [PDF]

Sci Rep
AlRaeesi I, El-Khazali R.
europepmc   +1 more source

Optimized super-twisting active disturbance rejection control based on nonlinear extended state observer for aircraft attitude stabilization. [PDF]

Sci Rep
Yazdiniya F, Ansarifar G.
europepmc   +1 more source

Fuzzy energy management using a chaotic model to improve fuel consumption of fuel cell-battery hybrid fixed-wing UAVs operating under uncertainty control. [PDF]

Sci Rep
Rostami M, Habibi P, Farajollahi A.
europepmc   +1 more source

The IMAP Observatory Overview. [PDF]

Space Sci Rev
Hegarty KP, Kubota S, Cully M, McComas DJ, Christian ER, Schwadron NA, Gkioulidou M, Bushman S, Collura C, Dauberman M, Drabenstadt C, Driesman A, Dubill A, Duffy B, Coleman E, Eng D, Ercol CJ, Gerger A, Hall R, Hahn J, Haque M, Hefter S, Jeong D, Jones D, Kelman J, Krupiarz C, Kujawa F, Lippe C, Matlin D, Monaco C, Myers D, Rivera Sepulveda E, Rodriguez D, Roufberg L, Scherrer J, Schwinger M, Shin A, Siddique F, Smith E, Smith R, Tapley M, Vernon S, Vigil C, Weidner S.   +43 more
europepmc   +1 more source

Do Insulin Pumps Dispense Unwanted or Incorrect Insulin Doses During a Flight? [PDF]

J Diabetes Sci Technol
Thomas A, Heinemann L.
europepmc   +1 more source

Harmonic adaptive fault-tolerant control for incipient and multiple faults of high mobility fighter. [PDF]

Sci Rep
Hu K, Wang Z, Wang J.
europepmc   +1 more source