Results 101 to 110 of about 194,546 (266)

Design and Construction of Spud Housing for Floating Dock

MATEC Web of Conferences, 2018
A floating dock is a type of pontoon for dry docking ships, possessing floodable buoyancy chambers. The Floating docks have more advantages than the other type of ship docking for maintenance.
Hasanudin Hasanudin, Yulianto Ardi Nugroho   +1 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A Compute-in-Memory Decoding Architecture for Posit-to-Floating-Point Conversion

IEEE Access
Modern computing systems are increasingly adopting low-precision floating-point formats to reduce memory overhead, particularly in large-scale applications such as large language models and scientific computing.
Jae Hyung Ko, Byung-Soo Kim, Taeho Hwang, Kyu Hyun Choi   +3 more
doaj   +1 more source

Paranoia.Ada: A diagnostic program to evaluate Ada floating-point arithmetic [PDF]

Many essential software functions in the mission critical computer resource application domain depend on floating point arithmetic. Numerically intensive functions associated with the Space Station project, such as emphemeris generation or the ...
Hjermstad, Chris
core   +1 more source

Bounded Floating Point: Identifying and Revealing Floating-Point Error

Advances in Science, Technology and Engineering Systems Journal, 2021
Alan A. Jorgensen, Las Vegas, Connie R. Masters, Ratan K. Guha, Andrew C. Masters   +4 more
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Masking FALCON’s Floating-Point Multiplication in Hardware

Transactions on Cryptographic Hardware and Embedded Systems
Floating-point arithmetic is a cornerstone in a wide array of computational domains, and it recently became a building block for the FALCON post-quantum digital signature algorithm.
Emre Karabulut, Aydin Aysu
doaj   +1 more source