Results 71 to 80 of about 194,546 (266)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Low-frequency shock response data analysis of underwater explosion test of 200-ton class floating shock platform

open access: yesZhongguo Jianchuan Yanjiu, 2018
[Objectives] In order to improve the standards of the anti-shock assessment testing of shipboard equipment, [Methods] the shock response data of the low-frequency vibration of a 200-ton floating shock platform is analyzed.
ZHANG Lei   +5 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Floating-Point Arithmetic [PDF]

open access: yes, 1982
The arithmetic instructions of SDC deal only with integers, and the Function Unit of chapter 10 can only perform arithmetic operations on integers. The calculations which computers are required to carry out may also involve real numbers, which are numbers with integral and fractional parts.
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The complexity of class polynomial computation via floating point approximations [PDF]

open access: yes, 2008
We analyse the complexity of computing class polynomials, that are an important ingredient for CM constructions of elliptic curves, via complex floating point approximations of their roots.
Enge, Andreas
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Robustness Analysis of Floating-Point Programs by Self-Composition

open access: yesJournal of Applied Mathematics, 2014
Robustness is a key property for critical systems that run in uncertain environments, to ensure that small input perturbations can cause only small output changes.
Liqian Chen   +4 more
doaj   +1 more source

Study of FPGA-based Error-controllable Floating-point Operation Accelerators [PDF]

open access: yesJisuanji gongcheng
Floating-point operations are fundamental operations in the field of High-Performance Computing(HPC). In the context of big data and cloud computing,the amount of data that HPC platforms need to process is continuously growing,and the round-off error of ...
GUAN Mingxiao, LIU Jiakun, ZHANG Hongrui, HE Anping
doaj   +1 more source

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