Results 81 to 90 of about 194,546 (266)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Enhancing CuFP Library with Self-Alignment Technique
ComputersHigh-Level Synthesis (HLS) tools have transformed FPGA development by streamlining digital design and enhancing efficiency. Meanwhile, advancements in semiconductor technology now support the integration of hundreds of floating-point units on a single ...
Fahimeh Hajizadeh +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Logic Design and Power Optimization of Floating-Point Multipliers. [PDF]
Comput Intell Neurosci, 2022 Bai N, Li H, Lv J, Yang S, Xu Y.
europepmc +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Lightweight Floating-Point Arithmetic: Case Study of Inverse Discrete Cosine Transform
EURASIP Journal on Advances in Signal Processing, 2002 To enable floating-point (FP) signal processing applications in low-power mobile devices, we propose lightweight floating-point arithmetic. It offers a wider range of precision/power/speed/area trade-offs, but is wrapped in forms that hide the ...
Fang Fang, Chen Tsuhan, Rutenbar Rob A
doaj +1 more source
Algorithm for output of floating-point numbers in fixed-point form
Journal of Applied Sciences and Environmental Management, 2006 Input/output of data items and information are very common operations performed on computer systems. Various data types require special ways to perform these operations on them. Floating-point numbers are no exceptions.
CB Ndeekor
doaj +1 more source
Optimal Architecture of Floating-Point Arithmetic for Neural Network Training Processors. [PDF]
Sensors (Basel), 2022 Junaid M, Arslan S, Lee T, Kim H.
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source