Results 171 to 180 of about 24,219 (260)

Geometry‐Encoded Soft Strain Sensing via Liquid‐Metal Transmission Lines

open access: yesAdvanced Science, EarlyView.
This study presents a liquid‐metal transmission‐line strain sensor that achieves intrinsic decoupling by encoding axial elongation into propagation delay. The time‐domain readout remains stable under complex off‐axis. This enables reliable, repeatable, real‐time elongation measurement in dynamic, multiaxial loading environments for wearable electronics,
Zhang Liu   +12 more
wiley   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

open access: yesAdvanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai   +10 more
wiley   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee   +3 more
wiley   +1 more source

Active Oscillations of Elastic Membranes Arising from the Coupling with a Catalytic Reaction

open access: yesAdvanced Science, EarlyView.
Coupling an elastic membrane to a catalytic reaction produces active oscillations that self‐sustain for hours: the membrane cyclically inflates and deflates as the reaction spontaneously activates and deactivates, without external power. Energy release is directly embodied in the oscillation dynamics, opening elasto‐chemical strategies for the physical
Alberto Comoretto   +5 more
wiley   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

open access: yesAdvanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han   +11 more
wiley   +1 more source

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