Results 121 to 130 of about 16,807,593 (396)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Enhanced flow rate prediction of disturbed pipe flow using a shallow neural network
FlowTrustworthy volumetric flow measurements are essential in many applications such as power plant controls or district heating systems. Flow metering under disturbed flow conditions, such as downstream of bends, is a challenge and leads to errors of up to ...
Christoph Wilms +4 more
doaj +1 more source
Event-plane flow analysis without non-flow effects
, 2011 The event-plane method, which is widely used to analyze anisotropic flow in nucleus-nucleus collisions, is known to be biased by nonflow effects,especially at high $p_t$.
Bilandzic, Ante +3 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 2015 The measurement of flow properties within fluid handling systems is of utmost importance for efficient operation and control of such systems. For single phase flow systems, extensive research has been carried out world over to diagnose the flow ...
Albarzenji, Dlir +4 more
core
Regional brain blood flow in man during acute changes in arterial blood gases [PDF]
, 2012 Chris K. Willie +10 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Consistent Video Saliency Using Local Gradient Flow Optimization and Global Refinement [PDF]
, 2015 Wenguan Wang, Jianbing Shen, Ling Shao
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source