Results 91 to 100 of about 1,828,109 (317)

Numerical analysis of cavitating flow characteristics in impeller of residual heat removal pump

open access: yes, 2016
In order to investigate internal cavitating flow characteristics of the impeller in residual heat removal pumps, the three-dimensional cavitating flow in a residual heat removal model pump is numerically calculated by using the homogeneous mixture ...
Yuan, Jianping   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Flow patterns and heat transfer for flow boiling in small to micro diameter tubes

open access: yes, 2008
An overview of the recent developments in the study of flow patterns and boiling heat transfer in small to micro diameter tubes is presented. The latest results of a long-term study of flow boiling of R134a in five vertical stainless steel tubes of ...
Karayiannis, TG   +3 more
core  

Aerodynamic investigations of ventilated brake discs. [PDF]

open access: yes, 2005
The heat dissipation and performance of a ventilated brake disc strongly depends on the aerodynamic characteristics of the flow through the rotor passages.
MacManus, David G., Parish, D.
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

FLOW CHARACTERISTICS OF SKIMMING FLOW IN A STEPPED CHANNEL

open access: yesPROCEEDINGS OF HYDRAULIC ENGINEERING, 2004
Recently, research onto the hydraulics of stepped chutes was driven by needs for better design guidelines (OHTSU and YASUDA 1997, CHANSON and TOOMBES 2002, BOES and HAGER 2003). Although stepped channel flows are characterized by intense turbulence and strong flow aeration, most studies did not investigate the turbulence characteristics. In this study,
YASUDA, Youichi   +2 more
openaire   +2 more sources

Flow Resistance and Heat Transfer Characteristics of Air in a Cross Flow Micro Heat Exchanger

open access: yes, 2002
Flow resistance and heat transfer characteristics of air flowing through a cross flow micro heat exchanger of stainless steel were experimentally investigated.
袁权   +5 more
core  

A new method for predicting the vortex induced aerodynamic characteristics of a body of revolution [PDF]

open access: yes, 1995
The problem of mathematically modelling the symmetric vortex pair formed on the lee side of a body of revolution at moderate incidence to the freestream direction is addressed with a view to predicting its aerodynamic characteristics.
Smith, Howard
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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