Results 71 to 80 of about 1,828,109 (317)

An investigation of the flow characteristics in the bootdeck region of a scale model notchback saloon vehicle [PDF]

open access: yes, 2007
The results of an experimental investigation of the bootdeck flow structure of a 36 per cent scale model notchback car are presented together with a general review of advanced laser diagnostic techniques suitable for large-scale wind tunnel flow ...
Garry, Kevin P.   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Characteristic Bending in Incompressible Flows

open access: yes
A B S T R A C TWe present the Characteristic Bending (CB) method, a general framework for advecting quantities under incompressible velocity fields. The method builds on standard semi-Lagrangian advection by interpreting the backward-in-time characteristic reconstruction as the construction of a reference map, a diffeomorphism between the current and ...
Matthew Blomquist   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Surface effects in flow boiling of R134a in microtubes

open access: yes, 2011
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 ElsevierThe inner surfaces of microtubes may be influenced strongly by the process of making them due to manufacturing ...
Tassos G. Karayiannis   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effect of single vanes on turbulent flow

open access: yesAdvances in Civil and Architectural Engineering
In response to growing environmental and ecological awareness, eco-friendly in-stream structures such as vanes have been implemented in different parts of the world to enhance stream conditions.
Sara Ahmadi Adli   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Characteristics and forces due to slugs in an 'S' shaped riser [PDF]

open access: yes, 2003
The characteristics and forces due to slugs in an 'S' shaped riser have been investigated. A series of experiments were carried out using the Cranfield University Riser Test Facility, using a 9.9m high riser. Single phase (water) and two phase (air and
Das, I. A. F.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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