Results 141 to 150 of about 521,952 (287)

Chemistry of Carbon Nanotubes in Flow

, 2014
The covalent chemistry of carbon nanostructures has put forth a wide variety of interesting derivatives that widen their potential as functional materials. However, the synthetic procedures that have been developed to functionalize the nanostructures may
CAROFIGLIO, TOMMASO, Tommaso Carofiglio, MENNA, ENZO, Alessandro Pace, MAITY, PRASENJIT, Michele Maggini, Prasenjit Maity, MAGGINI, MICHELE, Enzo Menna, Patrizio Salice, Emiliano Rossi   +10 more
core   +1 more source

P068 | ABNORMAL CD33 EXPRESSION ON BLAST CELLS PREDICTS ELN2022 ADVERSE RISK ACUTE MYELOID LEUKEMIA

Haematologica
Multiparametric flow cytometry (MFC) is useful at diagnosis and during therapy by measuring minimal residual disease in acute myeloid leukemia (AML) patients (pts).
D. Bertoli, V. Giustini, C. Giupponi, V. Quaresima, D. Moratto, C. Cattaneo, G. Rossi, A. Tucci, D. Brugnoni, G. Biasiotto, E. Borlenghi, M. Chiarini   +11 more
doaj  

Continuous Flow Chemistry: A Novel Technology for the Synthesis of Marine Drugs. [PDF]

Mar Drugs, 2023
Peña LF, González-Andrés P, Parte LG, Escribano R, Guerra J, Barbero A, López E.   +6 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Pushing the Limits of Solid-Phase Peptide Synthesis with Continuous Flow

Since its invention by Bruce Merrifield, solid-phase peptide synthesis has conventionally been performed in batch reactors. With systems created by Atherton, Dryland, and Sheppard in the 1980s, flow-chemistry techniques began to be applied to enhance ...
Steinauer, Angela, Mijalis, A. J., Schepartz, A., Pentelute, B. L.   +3 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Application of Flow Chemistry to the Direct Arylation of Thiophenes

, 2023
reservedOggigiorno, gli ariltiofeni sono ampiamente utilizzati come materiali elettronici organici e nell’ambito della farmaceutica. Questi composti sono preparati attraverso reazioni di cross-coupling, come quelle di Suzuki, Stille or Negishi.
PETRONILLI, ALESSANDRO
core  

Accelerated and Scalable C(sp3)–H Amination via Decatungstate Photocatalysis Using a Flow Photoreactor Equipped with High-Intensity LEDs

ACS Central Science, 2021
Ting Wan, Zhenghui Wen, Gabriele Laudadio, Luca Capaldo, Rob Lammers, Juan A. Rincón, Pablo García-Losada, Carlos Mateos, Michael O. Frederick, Rémy Broersma, Timothy Noël   +10 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source