Results 151 to 160 of about 6,410,488 (278)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Flow Chemistry as an Enabling Technology for Process-Intensified Amination Reactions: A Decadal Review. [PDF]

Molecules
Zhou F, Zhou Y, Wang P, Li Y, Li J, Xu H, Duanmu C.   +6 more
europepmc   +1 more source

Amide Bonds Meet Flow Chemistry: A Journey into Methodologies and Sustainable Evolution. [PDF]

ChemSusChem, 2022
Alfano AI, Lange H, Brindisi M.
europepmc   +1 more source

The Flow Theory chemistry

ABSTRACT:This paper presents a unified engineering model of the Universe based on the Flow Theory, which replaces the concept of an empty vacuum with a high-density stationary Medium (The Ocean). By introducing the Medium density coefficient (S) into 247 fundamental formulas, the author demonstrates that 40 previously separate scientific disciplines ...
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Modular Synthesis of Substituted Lactams via a Deoxygenative Photochemical Alkylation–Cyclization Cascade of Secondary Amides in Flow

JACS Au
Damiano Diprima, Thomas Terp Paulsen, Antonio Pulcinella, Stefano Bonciolini, Alexis L. Gabbey, Robin Stuhr, Thomas Bjørnskov Poulsen, Timothy Noël   +7 more
doaj   +1 more source

Advances in Flow Chemistry for Organolithium-Based Synthesis: A Process Perspective. [PDF]

Molecules
Zhou F, Zhou Y, Duanmu C, Li Y, Li J, Xu H, Wang P, Zhu K.   +7 more
europepmc   +1 more source

A comprehensive review of flow chemistry techniques tailored to the flavours and fragrances industries. [PDF]

Beilstein J Org Chem, 2021
Gambacorta G, Sharley JS, Baxendale IR.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Introducing the Flow Chemistry Network

CHIMIA, 2021
Benjamin Martin, Claudio Battilocchio, Agnieszka Ladosz   +2 more
doaj   +1 more source