Results 71 to 80 of about 1,472,154 (285)

Simulation of a hydrocarbon fueled scramjet exhaust [PDF]

open access: yes
Exhaust nozzle flow fields for a fully integrated, hydrocarbon burning scramjet were calculated for flight conditions of M (undisturbed free stream) = 4 at 6.1 km altitude and M (undisturbed free stream) = 6 at 30.5 km altitude.
Leng, J.
core   +1 more source

Effects of Surfactant Solubility on the Hydrodynamics of a Viscous Drop in a DC Electric Field

open access: yes, 2020
The physico-chemistry of surfactants (amphiphilic surface active agents) is often used to control the dynamics of viscous drops and bubbles. Surfactant sorption kinetics has been shown to play a critical role in the deformation of drops in extensional ...
Hu, W. -F.   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis

open access: yesBeilstein Journal of Organic Chemistry, 2017
Microreactor technology and flow chemistry could play an important role in the development of green and sustainable synthetic processes. In this review, some recent relevant examples in the field of flash chemistry, catalysis, hazardous chemistry and ...
Flavio Fanelli   +3 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Uniqsis – accessible flow chemistry

open access: yesGreen Processing and Synthesis, 2012
No abstract available.
Pergande Paul
doaj   +1 more source

Dual-Purpose Photometric-Conductivity Detector for Simultaneous and Sequential Measurements in Flow Analysis

open access: yesMolecules, 2020
This work presents a new dual-purpose detector for photometric and conductivity measurements in flow-based analysis. The photometric detector is a paired emitter–detector diode (PEDD) device, whilst the conductivity detection employs a capacitively ...
Thitirat Mantim   +5 more
doaj   +1 more source

Kinetics and mechanism of the reaction of acetonyl radical, CH3(CO)CH2, with Br2 [PDF]

open access: yes, 2013
The low pressure fast discharge flow method with laser induced fluorescence detection of CH3C(O)CH2 was employed to study the kinetics of the reaction CH3C(O)CH2 + Br2 → CH3C(O)CH2Br + Br (1) at 298, 323 and 365 K.
Brudnik, Katarzyna   +6 more
core   +1 more source

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