Results 101 to 110 of about 6,040,269 (294)

Numerical Investigation of the Coupling Effects of Pulsed H2 Jets and Nanosecond-Pulsed Actuation in Supersonic Crossflow

open access: yesAerospace
Numerical investigations were conducted to analyze the coupling effects of pulsed H2 jets and nanosecond-pulsed actuation (NS-SDBD) in a supersonic crossflow.
Keyu Li, Jiangfeng Wang
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Experiments of Lift-Bending Response on a Slender UAV Wing Structure with Control Surface under Extreme Flow Turbulence

open access: yesAerospace
The aeroelastic response of lightweight low-speed aircrafts with slender wings under extreme flow turbulence intensity is not well understood. Experiments on a commercial unmanned aerial vehicle (UAV) with a 3 m wingspan and aspect ratio of 13.6 were ...
Wolduamlak Ayele   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The development of passive flow control vortices [PDF]

open access: yes, 2004
Surface flow visualisation and Particle Image Velocimetry (PIV) were used to investigate the flow-field of sub-boundary layer vane vortex generators (VVGs) and steady jet vortex generators (SJVGs) in a separated flow at 20m/s.
Maina, Edward Ikinya
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Numerical Investigation of Stage Separation Control of Tandem Hypersonic Vehicles Based on Lateral Jet

open access: yesAerospace
The stage separation of hypersonic vehicles is critically challenged by severe aerodynamic interference, which induces significant attitude deviations and jeopardizes subsequent flight missions.
Wenhua Guo   +3 more
doaj   +1 more source

Flexible parylene actuator for micro adaptive flow control [PDF]

open access: yes, 2001
This paper describes the first flexible parylene electrostatic actuator valves intended for micro adaptive flow control for the future use on the wings of micro-air-vehicle (MAV).
Ho, C. M.   +3 more
core  

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