Results 161 to 170 of about 20,769,954 (368)

Axial compressor blades tip leakage flow control using natural aspiration. [PDF]

Sci Rep, 2023
Nejad PG, Zenouz RT.
europepmc   +1 more source

3D characterization of reattached flow on an airfoil with finite-span synthetic jet flow control [PDF]

arXiv
This paper synthesizes prior studies to develop a comprehensive three-dimensional description of reattached flow over an airfoil controlled by finite-span SJA arrays. When applied to a longer-span wing, the flow field exhibits three distinct regions: a directly controlled region, an unaffected region, and a transitional zone between them.
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

A MECHANISM FOR CONTROLLED CONTINUOUS FLOW OF NUTRIENT SOLUTIONS

, 1935
F. P. Mehrlich
openalex   +2 more sources

Discussion of “Spatially Varied Flow from Controlled Rainfall” [PDF]

, 1963
Roger L. Kuhlemeyer, David Warner
openalex   +1 more source

Flow Control: an Overview

, 2013
Journal Aerospace Lab, Issue 6, June 2013; ISSN: 2107 ...
openaire   +3 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Delayed Detached-Eddy Simulations of Aerodynamic Variability During Carrier-Based Aircraft Landing with a Domain Precursor Inflow Method

Journal of Marine Science and Engineering
Flight tests and wind tunnel experiments face difficulties in investigating the impact of aircraft carrier air-wake on the landing process. Meanwhile, numerical methods generally exhibit low overall computational efficiency in solving such problems.
Jiawei Fu, Ruifan Hu, Hong Wang, Ke Xu, Shuling Tian   +4 more
doaj   +1 more source

Nanomechanical Sensing for Mass Flow Control in Nanowire-Based Open Nanofluidic Systems. [PDF]

ACS Nano, 2023
Escobar JE, Molina J, Gil-Santos E, Ruz JJ, Malvar Ó, Kosaka PM, Tamayo J, San Paulo Á, Calleja M.   +8 more
europepmc   +1 more source