Results 121 to 130 of about 5,219,938 (357)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry

, 2022
J.J. Strouse, I. Ivnitski-Steele, Haider Khawaja, D. Perez, J. Ricci, T. Yao, W.S. Weiner, C.E. Schroeder, D.S. Simpson, B.E. Maki, K. Li, J.E. Golden, T.D. Foutz, A. Waller, A.M. Evangelisti, S.M. Young, S.E. Chavez, M.J. Garcia, O. Ursu, C.G. Bologa, M.B. Carter, V.M. Salas, K. Gouveia, G.P. Tegos, T.I. Oprea, B.S. Edwards, J. Aubé, R.S. Larson, L.A. Sklar   +28 more
openalex   +1 more source

P068 | ABNORMAL CD33 EXPRESSION ON BLAST CELLS PREDICTS ELN2022 ADVERSE RISK ACUTE MYELOID LEUKEMIA

Haematologica
Multiparametric flow cytometry (MFC) is useful at diagnosis and during therapy by measuring minimal residual disease in acute myeloid leukemia (AML) patients (pts).
D. Bertoli, V. Giustini, C. Giupponi, V. Quaresima, D. Moratto, C. Cattaneo, G. Rossi, A. Tucci, D. Brugnoni, G. Biasiotto, E. Borlenghi, M. Chiarini   +11 more
doaj  

A new method for detecting mycoplasma in cell cultures using colocalization of DNA and membrane staining

Biochemistry and Biophysics Reports
Mycoplasma often surreptitiously contaminates cell cultures without detection, mainly parasitizing the cell surface and thus interfering to some extent with the cells.
Mengyuan Li, Shan Liu, Cheng Zhou, Mengsi Sun, Yanjie Wang   +4 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Ole-Oxy, a Semi-Synthetic Analog of Oleuropein, Ameliorates Acute Skin and Colon Inflammation in Mice

Antioxidants
Inflammation is a key process in the pathophysiology of various diseases, with macrophages playing a central role in the inflammatory response. This study investigates the anti-inflammatory potential of a newly synthesized analog of oleuropein (OP), the ...
Nikolaos V. Angelis, Efthymios Paronis, Georgia Sarikaki, Antonios Kyriakopoulos, Anna Agapaki, Pigi-Maria Niotopoulou, Christina C. Knai, Pavlos Alexakos, Odyssefs Liagkas, Konstantinos F. Mavreas, Constantin N. Baxevanis, Alexios-Leandros Skaltsounis, Ourania E. Tsitsilonis, Ioannis K. Kostakis   +13 more
doaj   +1 more source

Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations

Applied and Environmental Microbiology, 1990
R. Amann, B. Binder, R. Olson, S. Chisholm, R. Devereux, D. Stahl   +5 more
semanticscholar   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

P07.06 Automated Flow Cytometry Test Distinguishes Cancer from Non-Cancer in Sputum with High Sensitivity and Specificity [PDF]

, 2021
Vivienne I. Rebel, Lydia H. Bederka, Pedro Henrique Xavier Nabuco de Araújo, Julián Córdoba Sánchez, M. Grayson, M.H. LeMieux, Jennifer Rebeles, Sizhen Lai, Xavier T. Reveles   +8 more
openalex   +1 more source