Results 81 to 90 of about 3,047,500 (291)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Free Flow and Discharge Characteristics of Trapezoidal-Shaped Weirs

open access: yesFluids, 2020
A number of studies have considered the effects of weir design variations on the free- and submerged-flow characteristics of trapezoidal broad-crested weirs. It appears that the hydraulics of short-crested weir flows have received little attention; thus,
Yebegaeshet T. Zerihun
doaj   +1 more source

Measurement and Calibration of A High-Sensitivity Microwave Power Sensor with An Attenuator [PDF]

open access: yes, 2014
In this paper, measurement and calibration of a high-sensitivity microwave power sensor through an attenuator is performed using direct comparison transfer technique.
Meng, Y. S., Shan, Y.
core   +1 more source

Distributed Collaborative Monitoring in Software Defined Networks

open access: yes, 2014
We propose a Distributed and Collaborative Monitoring system, DCM, with the following properties. First, DCM allow switches to collaboratively achieve flow monitoring tasks and balance measurement load. Second, DCM is able to perform per-flow monitoring,
Chen, Qian, Li, Xin, Yu, Ye
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Experimental Investigation of Aerodynamic Noise Generated by a Train-Car Gap

open access: yesJournal of Fluid Science and Technology, 2007
To investigate the mechanism of noise generation by a train-car gap, which is one of a major source of noise in Shinkansen trains, experiments were carried out in a wind tunnel using a 1/5-scale model train.
Fumio MIZUSHIMA   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Feedback Data Rate in PIV Measurement-Integrated Simulation

open access: yesJournal of Fluid Science and Technology, 2008
This paper deals with measurement-integrated (MI) simulation, which is based on the observer in dynamical system theory to obtain the exact and detailed information of real flows.
Takayuki YAMAGATA   +2 more
doaj   +1 more source

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