Results 101 to 110 of about 3,031,429 (300)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Electrothermal flow in Dielectrophoresis of Single-Walled Carbon Nanotubes
, 2007 We theoretically investigate the impact of the electrothermal flow on the dielectrophoretic separation of single-walled carbon nanotubes (SWNT). The electrothermal flow is observed to control the motions of semiconducting SWNTs in a sizeable domain near ...
A. Ramos +7 more
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Influence Of Neutron Capture Rates On The Rare Earth Region Of The r-Process Abundance Pattern
, 2012 We study the sensitivity of the r-process abundance pattern to neutron capture rates along the rare earth region (A~150 to A~180). We introduce the concepts of large nuclear flow and flow saturation which determine the neutron capture rates that are ...
D. D. Clayton +12 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Effect of the gas distribution system structure of a radial flow adsorber on gas distribution
工程科学学报, 2015 Uniform gas distribution in a radial flow adsorber plays an essential part in its performance. A 3D hydrodynamic and mathematical model of the radial flow adsorber was developed based on experimental studies.
WANG Hao-yu, LIU Ying-shu, MENG Yu
doaj +1 more source
Degeneration of flow pattern in acousto-elastic flow through sharp-edge microchannels. [PDF]
Ultrason Sonochem, 2023 Lu Y, Tan W, Liu Z, Mu S, Zhu G.
europepmc +1 more source
Landscape genetics and gene flow in the banana pathogenic fungus Mycosphaerella fijiensis [PDF]
, 2007 Among the different evolutionary forces driving population genetics, gene flow related to dispersal plays a major role in local adaptation processes. However very few studies on plant pathogenic fungi focussed on deciphering gene flow patterns at the ...
Carlier, Jean +7 more
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Blood flow pattern in eye before development of type 3 macular neovascularization. [PDF]
PLoS One, 2023 Yamaguchi S +4 more
europepmc +1 more source