Results 101 to 110 of about 3,049,820 (297)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fundamental flow problems of Jiyang Shale Oil in continental fault basins

open access: yesYouqi dizhi yu caishoulu
In view of the challenge of insufficient understanding of the flow mechanism of Jiyang Shale Oil in continental fault-depression basins, starting from the perspective of the generalized Darcy’s law, this paper demonstrated the dynamic evolution
YANG Yong   +10 more
doaj   +1 more source

Effects of EMS Induced Flow on Solidification and Solute Transport in Bloom Mold

open access: yesMetals, 2017
The flow, temperature, solidification, and solute concentration field in a continuous casting bloom mold were solved simultaneously by a multiphysics numerical model by considering the effect of in-mold electromagnetic stirring (M-EMS).
Qing Fang   +4 more
doaj   +1 more source

Landscape genetics and gene flow in the banana pathogenic fungus Mycosphaerella fijiensis [PDF]

open access: yes, 2007
Among the different evolutionary forces driving population genetics, gene flow related to dispersal plays a major role in local adaptation processes. However very few studies on plant pathogenic fungi focussed on deciphering gene flow patterns at the ...
Carlier, Jean   +7 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Some aspects of calculating flows about three-dimensional subsonic inlets [PDF]

open access: yes
Based on the potential flow model, computations were carried out for various three-dimensional inlet models. Some of these calculated results are presented in the forms of surface static pressure, flow angularity, surface flow pattern, and inlet flow ...
Kao, H. C.
core   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Numerical Study of Flow Pattern over Free Ogee Spillway (Case Study: Nimrod Reservoir Dam) [PDF]

open access: yesمهندسی منابع آب, 2018
Spillways are structures used for releasing the surplus floodwater in necessary conditions from storage dams. Ogee spillway is one of the most common and simplest structures. .
m p, z sh
doaj  

Blood flow pattern in eye before development of type 3 macular neovascularization. [PDF]

open access: yesPLoS One, 2023
Yamaguchi S   +4 more
europepmc   +1 more source

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