Results 131 to 140 of about 3,031,429 (300)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Some aspects of calculating flows about three-dimensional subsonic inlets [PDF]

open access: yes
Various three dimensional inlet models were calculated based on the potential flow model. Results are presented in the forms of surface static pressure, flow angularity, surface flow pattern, and inlet flow field.
Kao, H. C.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Experimental Study on Slug Flow of Submarine Pipelines in Wenchang Oilfield

open access: yesShiyou jixie, 2019
To eliminate the impact of severe slug flow on equipment and oilfield production, the second transportation line of Wenchang Oilfield Group is taken as the research object, and a simulation test device is established to study the flow state and parameter
Zhou Lichen
doaj  

Improving the flow pattern in the inlet forebay with diffusion angle in the Xuliu Irrigation Station

open access: yesGuan'gai paishui xuebao
【Objective】 The inlet forebay with a diffusion angle is a component of pump stations that helps distribute water flow evenly before it reaches the pump.
XU Pengfei   +5 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Modeling of Oil–Water Two-Phase Flow in Horizontal Pipes Using CFD for the Prediction of Flow Patterns

open access: yesEng
A computational fluid dynamics study of the horizontal oil–water flow was performed using the Eulerian–Eulerian and mixture multiphase models in conjunction with the realizable k–ε turbulence model for the characterization of flow patterns.
Octavio Andrés González-Estrada   +2 more
doaj   +1 more source

Information Flow Pattern in Early Mild Cognitive Impairment Patients. [PDF]

open access: yesFront Neurol, 2021
He H   +6 more
europepmc   +1 more source

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