Results 151 to 160 of about 1,670,401 (308)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
On the Convergence of Rate Based Flow Control
, 1995 Several issues in the design and analysis of rate based flow control algorithms are addressed in this paper. We suggest a new approach for rate based flow control algorithms which may be considered more "optimistic" than traditional approaches.
Zvi Ostfeld, Yishay Mansour, Yehuda Afek
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Pouring Flow Rate Control by Repetitive Control
Proceedings of the Japan Joint Automatic Control Conference, 2011 Kusakabe, Ryo, Yamada, Minoru
openaire +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Downhole Hydraulic Operated Multistage Flow Control Valve for Intelligent Well Completion System
Shiyou jixie, 2016 Downhole flow control valve is the core tool of intelligent well to realize intelligent production. The structure and working principle of downhole hydraulic operated multistage flow control valve applied in hydraulic-control fiber-monitor intelligent ...
Liao Chenglong +6 more
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Decoupled level and flow rate control of a two-tank system in beverage production: A comparative analysis of Fuzzy-PID and GA-PID for minimum time operation. [PDF]
PLoS OneKassie TD, Geremew MS, Chanie KA.
europepmc +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source