Results 91 to 100 of about 8,082,222 (392)

Experimental Investigation on Sandstone Permeability under Plastic Flow: Permeability Evolution Law with Stress Increment

open access: yesGeofluids, 2019
Permeability is an important physical property of rock. In rock and rock-like materials, permeability after yielding is closely related to plastic flow behavior.
Peng Gong   +4 more
doaj   +1 more source

The Network Link Outlier Factor (NLOF) for Fault Localization

open access: yesIEEE Open Journal of the Communications Society, 2020
We describe and experimentally evaluate the performance of our Network Link Outlier Factor (NLOF) for locating faults in communication networks. The NLOF is a unique outlier score assigned to each link in a network.
Christopher Mendoza, Michael P. Mcgarry
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Sequencing CONWIP flow-shops: Analysis and heuristics [PDF]

open access: yes
In this paper, we address the backlog sequencing problem in a flow-shop controlled by a CON\VIP production control system with the objective to minimise the make span We characterise the problem and analyse its similarities and differences with the ...
Framiúnan, Jose M.   +2 more
core  

Frozen shuffle update for an asymmetric exclusion process on a ring

open access: yes, 2011
We introduce a new rule of motion for a totally asymmetric exclusion process (TASEP) representing pedestrian traffic on a lattice. Its characteristic feature is that the positions of the pedestrians, modeled as hard-core particles, are updated in a fixed
Appert-Rolland C Cividini J Hilhorst H J   +15 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Towards computerizing intensive care sedation guidelines: design of a rule-based architecture for automated execution of clinical guidelines

open access: yesBMC Medical Informatics and Decision Making, 2010
Background Computerized ICUs rely on software services to convey the medical condition of their patients as well as assisting the staff in taking treatment decisions.
Kerckhove Wannes   +6 more
doaj   +1 more source

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