Results 91 to 100 of about 295,169 (217)
Shock Control on a Double-Fuselage Aircraft with a Natural Laminar Flow Wing
AerospaceThis paper presents the design of shock control bumps on a double-fuselage aircraft with a natural laminar flow (NLF) wing section. Both two-dimensional (2D) and three-dimensional (3D) bumps were investigated to identify the high-impact factors on both ...
Feng Deng +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
New Method for Kinematic Analysis of Gear Trains-Signal Flow Chart Method
Jixie chuandong, 1995 Signal flow chart and its simplified rule are introduced in this paper. Basis structure method for signal flow chart of gear train are discussed. Essential step for kinematic analysis of double gear train to apply signal flow chart method are studied ...
Yang Xinghai
doaj
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Tongxin xuebaoTo address the issue of slow end-to-end link establishment in software defined network (SDN) controllers, a novel dual-phase optimization method named ZHPro, based on zero-hop transmission and parallel flow rule deployment, was proposed.
ZHAO Baokang, LI Yikun, YANG Yu
doaj
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
A curve shortening flow rule for closed embedded plane curves with a prescribed rate of change in enclosed area. [PDF]
Proc Math Phys Eng Sci, 2016 Dallaston MC, McCue SW.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source