Results 101 to 110 of about 8,082,222 (392)

Relevance of Abelian Symmetry and Stochasticity in Directed Sandpiles

, 2008
We provide a comprehensive view on the role of Abelian symmetry and stochasticity in the universality class of directed sandpile models, in context of the underlying spatial correlations of metastable patterns and scars.
H. J. Jensen, Hang-Hyun Jo, Meesoon Ha
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Elasticity with a flow rule for geomaterials [PDF]

Materials Today Communications, 2019
Abstract The modern theory of elasticity and the first law of thermodynamics are cornerstones of engineering science that share the concept of reversibility. For four decades, researchers have noted that extrapolating the more commonly accepted empirical models of geomaterial stiffness violates the first law.
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A comparative study of applying Mason’s Rule in the case of flow-graphs and bond-graphs [PDF]

Journal of Electrical and Electronics Engineering, 2009
The paper presents two methods to analyzethe electric circuits using the flow-graphs and thebond-graphs studying the differences between thesemethods.As it can be noticed, the two methods are totallydifferent; their common point being Mason’s rule thatis
Adriana Grava
doaj  

Creating Data Flow Rules through Preferential Trade Agreements

, 2023
Abstract This chapter offers a mapping of developments in the area of digital trade governance with a deep dive on some more sophisticated templates that have been endorsed in recent years. It has become evident that PTAs have evolved into an important platform for rule-making in the area of digital trade, as well as that issues around ...
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The application of Riegels' rule and time-like damping to transonic flow calculations [PDF]

Finite difference relaxation solutions of the nonlinear small perturbation equations have proven reliable and successful in determining the transonic flowfields about thin airfoils.
Herron, D. L.
core   +1 more source