Results 91 to 100 of about 1,839,129 (302)

An analysis of the crossover between local and massive separation on airfoils [PDF]

Massive separation on airfoils operating at high Reynolds number is an important problem to the aerodynamicist, since its onset generally determines the limiting performance of an airfoil, and it can lead to serious problems related to aircraft control ...
Barnett, M., Carter, J. E.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Wind-tunnel tests of synthetic jet control effects on airfoil flow separation. [PDF]

Sci Rep, 2022
Zhao G, Zhao Q, Chen X.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Effects of Inflow Deflection Angle on the Stall Formation Mechanism and Flow Field Structure in a Vertical Axial-Flow Pump

Machines
The influence of inflow angle on the stall characteristics of a vertical axial flow pump is investigated numerically by solving the unsteady Reynolds-averaged Navier–Stokes equations.
Fan Meng, Qixiang Hu, Jinhe Liu, Yanjun Li, Guangjian Zhang, Jiaxing Lu   +5 more
doaj   +1 more source

Hydrophilic reentrant SLIPS enabled flow separation for rapid water harvesting. [PDF]

Proc Natl Acad Sci U S A, 2022
Guo Z, Boylan D, Shan L, Dai X.
europepmc   +1 more source

Surface flow visualization of separated flows on the forebody of an F-18 aircraft and wind-tunnel model [PDF]

A method of in-flight surface flow visualization similar to wind-tunnel-model oil flows is described for cases where photo-chase planes or onboard photography are not practical.
Banks, Daniel W., Fisher, David F., Richwine, David M.   +2 more
core   +1 more source

Separation of bacterial spores from flowing water in macro-scale cavities by ultrasonic standing waves

, 2010
The separation of micron-sized bacterial spores (Bacillus cereus) from a steady flow of water through the use of ultrasonic standing waves is demonstrated.
Costolo, M., Dionne, J., Lipkens, B., Rietman, Edward, Stevens, A.   +4 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Unsteady Flow and Loading Characteristics of Rotating Spheres During Underwater Ejection

Journal of Marine Science and Engineering
This study systematically investigates the evolution of the flow field and cavitation behavior during the underwater launch of a rotating sphere. By comparing surface pressure distribution, cavitation evolution, flow separation locations, and re-entrant ...
Hao Xu, Mingyang Wang, Zhou Zhou, Tiezhi Sun, Guiyong Zhang   +4 more
doaj   +1 more source