Results 111 to 120 of about 1,835,674 (303)

Separation of bacterial spores from flowing water in macro-scale cavities by ultrasonic standing waves

open access: yes, 2010
The separation of micron-sized bacterial spores (Bacillus cereus) from a steady flow of water through the use of ultrasonic standing waves is demonstrated.
Costolo, M.   +4 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Shock-induced separation of adiabatic turbulent boundary layers in supersonic axially symmetric internal flow [PDF]

open access: yes
An experimental investigation at Mach 4 of shock-induced turbulent boundary layer separation at the walls of axially symmetric flow passages is discussed, with particular emphasis placed on determining the shock strengths required for incipient ...
Childs, M. E., Page, R. J.
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Method and apparatus for detecting laminar flow separation and reattachment [PDF]

open access: yes, 1989
The invention is a method and apparatus for detecting laminar flow separation and flow reattachment of a fluid stream by simultaneously sensing and comparing a plurality of output signals, each representing the dynamic shear stress at one of an equal ...
Mangalam, Sivaramakrishnan M.   +1 more
core   +2 more sources

Localized defects in a cellular automaton model for traffic flow with phase separation

open access: yes, 2001
We study the impact of a localized defect in a cellular automaton model for traffic flow which exhibits metastable states and phase separation.
A. Pottmeier   +35 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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