Results 111 to 120 of about 1,839,129 (302)

An analysis method for multi-component airfoils in separated flow [PDF]

open access: yes
The multi-component airfoil program (Langley-MCARF) for attached flow is modified to accept the free vortex sheet separation-flow model program (Analytical Methods, Inc.-CLMAX).
Duorak, F. A., Maskew, B., Rao, B. M.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Oscillation Modes of Transonic Buffet on a Laminar Airfoil

open access: yesAerospace
This paper presents an experimental investigation of unsteady phenomena in shock wave/boundary-layer interaction on natural laminar flow airfoils at transonic speeds. Two airfoils of different relative thickness were studied over a Mach number range of M
Pavel Polivanov, Andrey Sidorenko
doaj   +1 more source

Computation of leading-edge vortex flows [PDF]

open access: yes
The simulation of the leading edge vortex flow about a series of conical delta wings through solution of the Navier-Stokes and Euler equations is studied. The occurrence, the validity, and the usefulness of separated flow solutions to the Euler equations
Newsome, R. W., Thomas, J. L.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

On the Aerodynamic Characteristics of the Aurel Persu Car

open access: yesEngineering Proceedings
This study investigates the aerodynamics of Romanian engineer Aurel Persu’s car through wind tunnel experiments involving force measurements, Particle Image Velocimetry (PIV), and CFD simulations.
Adrian Clenci   +3 more
doaj   +1 more source

Method and apparatus for detecting laminar flow separation and reattachment [PDF]

open access: yes, 1989
The invention is a method and apparatus for detecting laminar flow separation and flow reattachment of a fluid stream by simultaneously sensing and comparing a plurality of output signals, each representing the dynamic shear stress at one of an equal ...
Mangalam, Sivaramakrishnan M.   +1 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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