Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Flow Control of a Rim-Driven Propeller Using Vortex Generators for Enhanced Open-Water Performance
Journal of Marine Science and EngineeringRim-driven propellers (RDPs) have attracted renewed attention as an efficient propulsion concept for integrated electric propulsion systems, yet their structural configuration inherently limits duct geometry modification, and viscous losses associated ...
Ju Seong Bang +4 more
doaj +1 more source
High-Throughput Continuous-Flow Separation in a Micro Free-Flow Electrophoresis Glass Chip Based on Laser Microfabrication. [PDF]
Sensors (Basel), 2022 Zhang A +7 more
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
On the Aerodynamic Characteristics of the Aurel Persu Car
Engineering ProceedingsThis study investigates the aerodynamics of Romanian engineer Aurel Persu’s car through wind tunnel experiments involving force measurements, Particle Image Velocimetry (PIV), and CFD simulations.
Adrian Clenci +3 more
doaj +1 more source
Quantification of the Intraglottal Pressure Induced by Flow Separation Vortices Using Large Eddy Simulation. [PDF]
J Voice, 2021 Farbos de Luzan C +3 more
europepmc +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Oscillation Modes of Transonic Buffet on a Laminar Airfoil
AerospaceThis paper presents an experimental investigation of unsteady phenomena in shock wave/boundary-layer interaction on natural laminar flow airfoils at transonic speeds. Two airfoils of different relative thickness were studied over a Mach number range of M
Pavel Polivanov, Andrey Sidorenko
doaj +1 more source