Results 121 to 130 of about 1,839,129 (302)

Design of High-Efficiency Jet Lift Enhancement for Flaps Under Propeller Slipstream Influence

open access: yesAerospace
Both propeller slipstream and flap jet flow can significantly increase the aircraft lift coefficient. To establish design principles for efficient lift enhancement via jet flow under the influence of slipstream, wind tunnel experiments are conducted on a
Yan Shao   +5 more
doaj   +1 more source

Control of vortical separation on conical bodies [PDF]

open access: yes
In a variety of aeronautical applications, the flow around conical bodies at incidence is of interest. Such applications include, but are not limited to, highly maneuverable aircraft with delta wings, the aerospace plane and nose portions of spike inlets.
Mourtos, Nikos J., Roberts, Leonard
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Numerical Analysis of Ejector Flow Performance for High-Altitude Simulation

open access: yesAerospace
In this study we perform a computational numerical analysis to examine the flow characteristics of a system composed of a rocket engine, supersonic diffuser, and ejector system.
Chae-Hyoung Kim, Chang-Su Park
doaj   +1 more source

A computational model for three-dimensional incompressible wall jets with large cross flow [PDF]

open access: yes, 1979
A computational model for the flow field of three dimensional incompressible wall jets prototypic of thrust augmenting ejectors with large cross flow is presented.
Malmuth, N. D.   +2 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Control on Flow Separation over a Cylinder by a Ferrofluid Film Adsorbed by a Magnet

open access: yesInventions
Flow separation can lead to increased resistance and vibration generation, which is a difficult problem that cannot be ignored in engineering. In this paper, we propose a method of controlling flow separation by adsorbing ferrofluid onto the surface of a
Chunyun Wei   +5 more
doaj   +1 more source

An evaluation of three two-dimensional computational fluid dynamics codes including low Reynolds numbers and transonic Mach numbers [PDF]

open access: yes
Full-potential, Euler, and Navier-Stokes computational fluid dynamics (CFD) codes were evaluated for use in analyzing the flow field about airfoils sections operating at Mach numbers from 0.20 to 0.60 and Reynolds numbers from 500,000 to 2,000,000.
Cliff, Susan E., Hicks, Raymond M.
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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