Results 71 to 80 of about 1,835,674 (303)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The development of passive flow control vortices [PDF]

open access: yes, 2004
Surface flow visualisation and Particle Image Velocimetry (PIV) were used to investigate the flow-field of sub-boundary layer vane vortex generators (VVGs) and steady jet vortex generators (SJVGs) in a separated flow at 20m/s.
Maina, Edward Ikinya
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Numerical Study on the Influence of Inlet Turbulence Intensity on Turbine Cascades

open access: yesAerospace
The turbulence intensity of the high-pressure turbine inlet plays an important role in the development of secondary flow and boundary layer evolution in the turbine passage.
Xuan Wu   +3 more
doaj   +1 more source

Directed percolation in aerodynamics: resolving laminar separation bubble on airfoils [PDF]

open access: yes, 2017
In nature, phase transitions prevail amongst inherently different systems, while frequently showing a universal behavior at their critical point. As a fundamental phenomenon of fluid mechanics, recent studies suggested laminar-turbulent transition ...
Gülker, Gerd   +4 more
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

EnKF Unsteady Data Assimilation of the Flow Separation Around an Aerofoil

open access: yes气体物理
To improve the prediction performance of the RANS model for flow separation, the model constants of the SST turbulence model were recalibrated using the unsteady ensemble Kalman filter (EnKF) data assimilation (DA) combined with the particle image ...
Yuyao ZHANG, Chuangxin HE, Yingzheng LIU
doaj   +1 more source

Intelligent Prediction of Separated Flow Dynamics using Machine Learning [PDF]

open access: yesJournal of Applied Fluid Mechanics
Understanding separated flow dynamics is crucial for implementing effective flow control techniques. These techniques help mitigate adverse effects on vehicle performance and environmental pollution.
S. Kouah, F. Fadla, M. Roudane
doaj   +1 more source

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